High prevalence of carbapenem-resistant Pseudomonas aeruginosa and identification of a novel VIM-type metallo-β-lactamase, VIM-92, in clinical isolates from northern China

High prevalence of carbapenem-resistant Pseudomonas aeruginosa and identification of a novel VIM-type metallo-β-lactamase, VIM-92, in clinical isolates from northern China

Carbapenem-resistant Pseudomonas aeruginosa (CRPA) has become a serious global health concern due to the limited treatment options. The primary resistance mechanism in CRPA involves the production of metallo-β-lactamases (MBLs), making MBL-producing P. aeruginosa a significant component of CRPA case...

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Bibliographic Details
Main Authors: Linbo Zhao, Jiekun Pu, Yunning Liu, Heng Cai, Meijuan Han, Yunsong Yu, Jianhua Tang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
epidemiological investigation
metallo-β-lactamase
VIM-92
plasmid
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2025.1543509/full
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