Synthesis and Anti-Inflammatory Activity of Pyrazolines

Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate...

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Main Authors: B. Ramesh, T. Sumana
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/731675
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author B. Ramesh
T. Sumana
author_facet B. Ramesh
T. Sumana
author_sort B. Ramesh
collection DOAJ
description Some new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.
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institution OA Journals
issn 0973-4945
2090-9810
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publishDate 2010-01-01
publisher Wiley
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series E-Journal of Chemistry
spelling doaj-art-e1d2d8a7b45d4d5e95dcac8752150c2f2025-08-20T02:21:38ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017251451610.1155/2010/731675Synthesis and Anti-Inflammatory Activity of PyrazolinesB. Ramesh0T. Sumana1Department of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, IndiaDepartment of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H. Road, Tumkur-572102, Karnataka, IndiaSome new pyrazoline derivatives were synthesized by reacting chalcones of 2-acetyl thiophene with phenyl hydrazine hydrochloride in the presence of alcohol. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.http://dx.doi.org/10.1155/2010/731675
spellingShingle B. Ramesh
T. Sumana
Synthesis and Anti-Inflammatory Activity of Pyrazolines
E-Journal of Chemistry
title Synthesis and Anti-Inflammatory Activity of Pyrazolines
title_full Synthesis and Anti-Inflammatory Activity of Pyrazolines
title_fullStr Synthesis and Anti-Inflammatory Activity of Pyrazolines
title_full_unstemmed Synthesis and Anti-Inflammatory Activity of Pyrazolines
title_short Synthesis and Anti-Inflammatory Activity of Pyrazolines
title_sort synthesis and anti inflammatory activity of pyrazolines
url http://dx.doi.org/10.1155/2010/731675
work_keys_str_mv AT bramesh synthesisandantiinflammatoryactivityofpyrazolines
AT tsumana synthesisandantiinflammatoryactivityofpyrazolines