Absence of sex differences in serotonergic control of orbitofrontal cortex neuronal activity

Abstract The orbitofrontal cortex (OFC) is a brain region involved in cognitive processing, especially in tasks that require flexibility in decision-making. Serotonin (5-HT) plays a critical role in mediating OFC-dependent behavior, primarily through its actions at both 5-HT1 and 5-HT2 receptors. Th...

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Bibliographic Details
Main Authors: Kailin M. Mooney, Alexander F. Hoffman, Carl R. Lupica
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-11208-2
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