Development of a novel bivalent vaccine candidate against hepatitis A virus and rotavirus using reverse vaccinology and immunoinformatics

The hepatitis A virus (HAV) and rotavirus are mainly transmitted through fecal-oral and person-to-person contact, and cause severe gastrointestinal complications and liver disease. This work used reverse vaccinology and immunoinformatic methods to create a novel bivalent vaccine against rotavirus an...

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Bibliographic Details
Main Authors: Hassan Yarmohammadi, Abbas Akhavan Sepahi, Mojtaba Hamidi-fard, Mohammadreza Aghasadeghi, Golnaz Bahramali
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Virus Eradication
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Online Access:http://www.sciencedirect.com/science/article/pii/S2055664024001936
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