Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis

Background/Aims This study aimed to investigate co-occurrence and clinical characteristics of sexually transmitted infections (STIs) and pelvic inflammatory disease (PID) in women hospitalized for acute pyelonephritis (APN). Methods This single-center retrospective study reviewed medical records of...

Full description

Saved in:
Bibliographic Details
Main Authors: Mi-Hee Kim, Hyojin Ahn, Soyeon Kang, Ahra Lee, Seong-Heon Wie
Format: Article
Language:English
Published: The Korean Association of Internal Medicine 2025-05-01
Series:The Korean Journal of Internal Medicine
Subjects:
Online Access:http://kjim.org/upload/kjim-2024-213.pdf
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850132136209678336
author Mi-Hee Kim
Hyojin Ahn
Soyeon Kang
Ahra Lee
Seong-Heon Wie
author_facet Mi-Hee Kim
Hyojin Ahn
Soyeon Kang
Ahra Lee
Seong-Heon Wie
author_sort Mi-Hee Kim
collection DOAJ
description Background/Aims This study aimed to investigate co-occurrence and clinical characteristics of sexually transmitted infections (STIs) and pelvic inflammatory disease (PID) in women hospitalized for acute pyelonephritis (APN). Methods This single-center retrospective study reviewed medical records of inpatients with APN from January 2019 to February 2023 and identified records of 142 patients who were referred to a gynecologist to evaluate gynecological diseases including STIs. Results Of the 142 patients, 47 were tested positive for sexually transmitted pathogens in nucleic acid amplification testing, confirming the presence of STIs. In patients with APN, those with STIs were more likely to have lower abdominal pain or cervical motion tenderness (CMT) on pelvic examination and leukocytosis (> 14.5 × 109/L) than those without STIs. Of the 93 patients who underwent pelvic examination, 34 had CMT with one or more of additional criteria for the clinical diagnosis of PID, such as abnormal vaginal discharge and leukorrhea confirmed by microscopic examination, which could be clinically diagnosed as PID. Conclusions In sexually active women with APN, it is important to evaluate the possibility of STIs and PID, considering several risk factors such as lower abdominal pain, abnormal vaginal discharge, CMT, and leukocytosis.
format Article
id doaj-art-e1b8f8d3aa5f4758b194da3d1da45793
institution OA Journals
issn 1226-3303
2005-6648
language English
publishDate 2025-05-01
publisher The Korean Association of Internal Medicine
record_format Article
series The Korean Journal of Internal Medicine
spelling doaj-art-e1b8f8d3aa5f4758b194da3d1da457932025-08-20T02:32:18ZengThe Korean Association of Internal MedicineThe Korean Journal of Internal Medicine1226-33032005-66482025-05-0140348249010.3904/kjim.2024.213171022Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritisMi-Hee Kim0Hyojin Ahn1Soyeon Kang2Ahra Lee3Seong-Heon Wie4 Division of Infectious Diseases, Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Infectious Diseases Department of Internal Medicine, Daejeon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Obstetrics and Gynecology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Department of Obstetrics and Gynecology, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea Division of Infectious Diseases, Department of Internal Medicine, St. Vincent’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, KoreaBackground/Aims This study aimed to investigate co-occurrence and clinical characteristics of sexually transmitted infections (STIs) and pelvic inflammatory disease (PID) in women hospitalized for acute pyelonephritis (APN). Methods This single-center retrospective study reviewed medical records of inpatients with APN from January 2019 to February 2023 and identified records of 142 patients who were referred to a gynecologist to evaluate gynecological diseases including STIs. Results Of the 142 patients, 47 were tested positive for sexually transmitted pathogens in nucleic acid amplification testing, confirming the presence of STIs. In patients with APN, those with STIs were more likely to have lower abdominal pain or cervical motion tenderness (CMT) on pelvic examination and leukocytosis (> 14.5 × 109/L) than those without STIs. Of the 93 patients who underwent pelvic examination, 34 had CMT with one or more of additional criteria for the clinical diagnosis of PID, such as abnormal vaginal discharge and leukorrhea confirmed by microscopic examination, which could be clinically diagnosed as PID. Conclusions In sexually active women with APN, it is important to evaluate the possibility of STIs and PID, considering several risk factors such as lower abdominal pain, abnormal vaginal discharge, CMT, and leukocytosis.http://kjim.org/upload/kjim-2024-213.pdfpyelonephritispelvic inflammatory diseasesexually transmitted infection
spellingShingle Mi-Hee Kim
Hyojin Ahn
Soyeon Kang
Ahra Lee
Seong-Heon Wie
Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
The Korean Journal of Internal Medicine
pyelonephritis
pelvic inflammatory disease
sexually transmitted infection
title Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
title_full Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
title_fullStr Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
title_full_unstemmed Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
title_short Clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
title_sort clinical approach to sexually transmitted infections and pelvic inflammatory disease in women with acute pyelonephritis
topic pyelonephritis
pelvic inflammatory disease
sexually transmitted infection
url http://kjim.org/upload/kjim-2024-213.pdf
work_keys_str_mv AT miheekim clinicalapproachtosexuallytransmittedinfectionsandpelvicinflammatorydiseaseinwomenwithacutepyelonephritis
AT hyojinahn clinicalapproachtosexuallytransmittedinfectionsandpelvicinflammatorydiseaseinwomenwithacutepyelonephritis
AT soyeonkang clinicalapproachtosexuallytransmittedinfectionsandpelvicinflammatorydiseaseinwomenwithacutepyelonephritis
AT ahralee clinicalapproachtosexuallytransmittedinfectionsandpelvicinflammatorydiseaseinwomenwithacutepyelonephritis
AT seongheonwie clinicalapproachtosexuallytransmittedinfectionsandpelvicinflammatorydiseaseinwomenwithacutepyelonephritis