The essential calcium channel of sperm CatSper is temperature-gated

Abstract The flagellar calcium channel CatSper is essential for male fertility, as it regulates calcium influx to trigger the hyperactive motility required for sperm to fertilize the egg. Precise activation of CatSper is critical, as premature activation can impair sperm function. While optimal temp...

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Bibliographic Details
Main Authors: Dilip K. Swain, Citlalli Vergara, Júlia Castro-Arnau, Polina V. Lishko
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58824-0
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