The genotypical characteristic of M. tuberculosis — aetiological agents of acute progressive destructive pulmonary tuberculosis

The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulati...

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Main Authors: O. V. Voronkova, O. I. Urazova, R. R. Khasanova, V. V. Novitsky, Ye. G. Churina, I. O. Naslednikova, O. V. Filinyuk, V. A. Serebryakova, Yu. V. Kolobovnikova
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2011-02-01
Series:Бюллетень сибирской медицины
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Online Access:https://bulletin.ssmu.ru/jour/article/view/1308
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Summary:The results of 77 M. tuberculosis clinical isolates genetic typing, allocated from patients with extensive destructive infiltrative and disseminated pulmonary tuberculosis are presented in the article. It is established that among genetically non-uniform Mycobacterium tuberculosis strains, circulating in Tomsk and the Tomsk Region, and causing acute progressive destructive pulmonary tuberculosis, 19% show multi drag resistance. Beijing family strains make 27% from the general population, have a high clusterization index (74%), level of their multi drag resistance in 3 times exceeds that at «not Beijing» strains for which the share of clustering strains makes 11%.
ISSN:1682-0363
1819-3684