Detection of hypervirulent Klebsiella pneumoniae (hvKp) strains directly from spiked blood cultures using a commercial Loop-Mediated isothermal amplification (LAMP) assay

Detection of hypervirulent Klebsiella pneumoniae (hvKp) strains directly from spiked blood cultures using a commercial Loop-Mediated isothermal amplification (LAMP) assay

Abstract Background Hypervirulent K. pneumoniae (hvKp) strains are characterized by their enhanced ability to evade immune responses and disseminate systemically. Rapid identification of hvKp strains is critical for guiding clinical management and implementing effective infection control measures. L...

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Main Authors: Domingo Fernández Vecilla, Jorge Rodríguez Grande, Nuria Fraile Valcárcel, Zaira Moure García, Sergio García Fernández, María Siller Ruiz, María Pía Roiz Mesones, José Luis Díaz de Tuesta del Arco, Mikel Joseba Urrutikoetxea Gutiérrez, María Catalina Lomoro, María Carmen Fariñas, Alain Ocampo-Sosa
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
LAMP
Hypervirulent
Klebsiella pneumoniae
Diagnosis
Spiked blood cultures
Online Access:https://doi.org/10.1186/s12941-025-00817-4
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