Multitarget inhibition of CDK2, EGFR, and tubulin by phenylindole derivatives: Insights from 3D-QSAR, molecular docking, and dynamics for cancer therapy.

Cancer remains one of the leading causes of death globally, presenting significant challenges to healthcare systems due to its complexity and the limitations of current therapeutic strategies. Despite advancements in anticancer drug development, monotherapies often fail to provide long-term efficacy...

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Bibliographic Details
Main Authors: Khadijah M Al-Zaydi, Soukayna Baammi, Mohamed Moussaoui
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0326245
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