Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction

Poly(dimethylsiloxane) silicones have found many applications in biomedical devices, whereas their surface hydrophobicity always brings about unexpected bioadhesion, causing complications of the implanted biomedical devices. In this work, surface-initiated reversible addition-fragmentation chain tra...

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Main Authors: Junmei Tang, Yuemei Han, Hao Chen, Quankui Lin
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2016/8458752
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author Junmei Tang
Yuemei Han
Hao Chen
Quankui Lin
author_facet Junmei Tang
Yuemei Han
Hao Chen
Quankui Lin
author_sort Junmei Tang
collection DOAJ
description Poly(dimethylsiloxane) silicones have found many applications in biomedical devices, whereas their surface hydrophobicity always brings about unexpected bioadhesion, causing complications of the implanted biomedical devices. In this work, surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to generate PEG brushes on silicone surface, obtaining highly hydrophilic surface coatings. Such PEG brush coated silicone presents excellent antifouling to protein, cells, and bacteria, which may have great potential in implantable biomaterial surface modifications.
format Article
id doaj-art-e185cce6919947dbb23a11f0d9ed3285
institution Kabale University
issn 1687-9422
1687-9430
language English
publishDate 2016-01-01
publisher Wiley
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series International Journal of Polymer Science
spelling doaj-art-e185cce6919947dbb23a11f0d9ed32852025-02-03T05:48:29ZengWileyInternational Journal of Polymer Science1687-94221687-94302016-01-01201610.1155/2016/84587528458752Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface ConstructionJunmei Tang0Yuemei Han1Hao Chen2Quankui Lin3School of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, ChinaSchool of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, ChinaSchool of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, ChinaSchool of Ophthalmology & Optometry, Eye Hospital, Wenzhou Medical University, Wenzhou 325027, ChinaPoly(dimethylsiloxane) silicones have found many applications in biomedical devices, whereas their surface hydrophobicity always brings about unexpected bioadhesion, causing complications of the implanted biomedical devices. In this work, surface-initiated reversible addition-fragmentation chain transfer (SI-RAFT) polymerization was utilized to generate PEG brushes on silicone surface, obtaining highly hydrophilic surface coatings. Such PEG brush coated silicone presents excellent antifouling to protein, cells, and bacteria, which may have great potential in implantable biomaterial surface modifications.http://dx.doi.org/10.1155/2016/8458752
spellingShingle Junmei Tang
Yuemei Han
Hao Chen
Quankui Lin
Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
International Journal of Polymer Science
title Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
title_full Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
title_fullStr Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
title_full_unstemmed Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
title_short Bottom-Up Fabrication of PEG Brush on Poly(dimethylsiloxane) for Antifouling Surface Construction
title_sort bottom up fabrication of peg brush on poly dimethylsiloxane for antifouling surface construction
url http://dx.doi.org/10.1155/2016/8458752
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AT yuemeihan bottomupfabricationofpegbrushonpolydimethylsiloxaneforantifoulingsurfaceconstruction
AT haochen bottomupfabricationofpegbrushonpolydimethylsiloxaneforantifoulingsurfaceconstruction
AT quankuilin bottomupfabricationofpegbrushonpolydimethylsiloxaneforantifoulingsurfaceconstruction