Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma
Objective. To identify the risk factors for cervical lymph node metastasis (CLNM) and the feasibility of prophylactic central lymph node dissection. Methods. The characteristics of 1107 patients were extracted and analyzed. Univariate and multivariate analyses were used to identify risk factors asso...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2021/6635686 |
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| author | Yifan Chen Shuo Chen Xiaoying Lin Xiangqing Huang Xiaofang Yu Juying Chen |
| author_facet | Yifan Chen Shuo Chen Xiaoying Lin Xiangqing Huang Xiaofang Yu Juying Chen |
| author_sort | Yifan Chen |
| collection | DOAJ |
| description | Objective. To identify the risk factors for cervical lymph node metastasis (CLNM) and the feasibility of prophylactic central lymph node dissection. Methods. The characteristics of 1107 patients were extracted and analyzed. Univariate and multivariate analyses were used to identify risk factors associated with lymph node metastasis. The relationship between the central lymph node dissection (CLND) and lateral lymph node metastasis (LLNM) was analyzed using the correlation analysis. Results. The probability of CLNM was closely related to the male gender, age <55, and the increase of tumor size. Those patients with an increase in tumor size and CLNM were extremely prone to LLNM. Also, LLNM was more likely to happen in those with the more positive central lymph nodes. Routine prophylactic central lymph node dissection (P-CLND) did not increase the risk of complications. Conclusion. P-CLND should be considered as a reasonable surgical treatment for PTC. |
| format | Article |
| id | doaj-art-e1715497a86849329a20bce880c6ac49 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-e1715497a86849329a20bce880c6ac492025-02-03T01:29:18ZengWileyInternational Journal of Endocrinology1687-83371687-83452021-01-01202110.1155/2021/66356866635686Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid CarcinomaYifan Chen0Shuo Chen1Xiaoying Lin2Xiangqing Huang3Xiaofang Yu4Juying Chen5Department of General Surgery, South Branch of Fujian Provincial Hospital, Fuzhou 350000, Fujian, ChinaProvincial Clinical Medical College of Fujian Medical University, Fuzhou 350000, Fujian, ChinaDepartment of General Surgery, South Branch of Fujian Provincial Hospital, Fuzhou 350000, Fujian, ChinaDepartment of General Surgery, South Branch of Fujian Provincial Hospital, Fuzhou 350000, Fujian, ChinaDepartment of General Surgery, South Branch of Fujian Provincial Hospital, Fuzhou 350000, Fujian, ChinaDepartment of General Surgery, South Branch of Fujian Provincial Hospital, Fuzhou 350000, Fujian, ChinaObjective. To identify the risk factors for cervical lymph node metastasis (CLNM) and the feasibility of prophylactic central lymph node dissection. Methods. The characteristics of 1107 patients were extracted and analyzed. Univariate and multivariate analyses were used to identify risk factors associated with lymph node metastasis. The relationship between the central lymph node dissection (CLND) and lateral lymph node metastasis (LLNM) was analyzed using the correlation analysis. Results. The probability of CLNM was closely related to the male gender, age <55, and the increase of tumor size. Those patients with an increase in tumor size and CLNM were extremely prone to LLNM. Also, LLNM was more likely to happen in those with the more positive central lymph nodes. Routine prophylactic central lymph node dissection (P-CLND) did not increase the risk of complications. Conclusion. P-CLND should be considered as a reasonable surgical treatment for PTC.http://dx.doi.org/10.1155/2021/6635686 |
| spellingShingle | Yifan Chen Shuo Chen Xiaoying Lin Xiangqing Huang Xiaofang Yu Juying Chen Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma International Journal of Endocrinology |
| title | Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma |
| title_full | Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma |
| title_fullStr | Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma |
| title_full_unstemmed | Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma |
| title_short | Clinical Analysis of Cervical Lymph Node Metastasis Risk Factors and the Feasibility of Prophylactic Central Lymph Node Dissection in Papillary Thyroid Carcinoma |
| title_sort | clinical analysis of cervical lymph node metastasis risk factors and the feasibility of prophylactic central lymph node dissection in papillary thyroid carcinoma |
| url | http://dx.doi.org/10.1155/2021/6635686 |
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