Interferon Alpha on Expression of hTERT mRNA in Peripheral Blood Mononuclear Cells of Patients with Chronic Hepatitis B

Interferon Alpha on Expression of hTERT mRNA in Peripheral Blood Mononuclear Cells of Patients with Chronic Hepatitis B

Cell division is closely related to telomerase activity (hTERT mRNA). Lower expression of lymphocitic hTERT mRNA may easily cause cell aging, which is not beneficial to maintaining a durable lymphocyte division. To date, there is no study to investigate IFNα therapy on hTERT mRNA expression in PBMCs...

Full description

Saved in:

Bibliographic Details
Main Authors:	Chuan-wu Zhu, Ming Chen, Xiang-rong Luo, Hai-yan Wang, Li-hua Wang, Jian-hong Wu, Ming Li, Xue-hua Zhang, Wei Zhu, Jian-zhong Ye, Feng Qian
Format:	Article
Language:	English
Published:	Wiley 2011-01-01
Series:	Clinical and Developmental Immunology
Online Access:	http://dx.doi.org/10.1155/2011/920146
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

An improved model for the hTERT promoter quadruplex.
by: Jonathan B Chaires, et al.
Published: (2014-01-01)

Pathology of Hepatocellular Carcinoma and Tumor-Bearing Liver Tissue in Association with hTERT Promoter Mutation
by: Anne Kristin Fischer, et al.
Published: (2023-01-01)

Antiproliferative Effects of Ferulic, Coumaric, and Caffeic Acids in HepG2 Cells by hTERT Downregulation
by: Afsoon Afshari, et al.
Published: (2022-01-01)

Simultaneous Down-Regulation of Intracellular MicroRNA-21 and hTERT mRNA Using AS1411-Functionallized Gold Nanoprobes to Achieve Targeted Anti-Tumor Therapy
by: Qinghong Ji, et al.
Published: (2024-12-01)

hTERT-Immortalized Bone Mesenchymal Stromal Cells Expressing Rat Galanin via a Single Tetracycline-Inducible Lentivirus System
by: Ke An, et al.
Published: (2017-01-01)

Inhibition of Human Telomerase Reverse Transcritpase (hTERT) and Telomerase Activity by Curcumin in Human Mammary Epithelial and Breast Carcinoma Cell Lines
by: Chappail Ramachandran, et al.
Published: (2001-01-01)

The role of m6A regulators mRNA expression in peripheral blood mononuclear cells in chronic hepatitis B: a novel diagnostic and prognostic indicator
by: Xiu Han, et al.
Published: (2025-07-01)

Deletion of gE in Herpes Simplex Virus 1 Leads to Increased Extracellular Virus Production and Augmented Interferon Alpha Production by Peripheral Blood Mononuclear Cells
by: Manon Claeys, et al.
Published: (2024-12-01)

Peripheral Blood Mononuclear Cell Gene Expression Remains Broadly Altered Years after Successful Interferon-Based Hepatitis C Virus Treatment
by: Paul Ravi Waldron, et al.
Published: (2015-01-01)

Long Noncoding RNAs and mRNA Regulation in Peripheral Blood Mononuclear Cells of Patients with Chronic Obstructive Pulmonary Disease
by: Xiaoyan Qu, et al.
Published: (2018-01-01)

Pegylated Interferon Alpha for Chronic Hepatitis B Virus Infection
by: Joana Vasconcelos, et al.
Published: (2022-01-01)

Transcriptional response to hepatitis C virus infection and interferon‐alpha treatment in the human liver
by: Tujana Boldanova, et al.
Published: (2017-03-01)

Long Term Follow-Up of Patients with Chronic Hepatitis C Treated with Alpha Interferon
by: Jane D Collier, et al.
Published: (2000-01-01)

Interferon‐beta signaling in retinal mononuclear phagocytes attenuates pathological neovascularization
by: Anika Lückoff, et al.
Published: (2016-05-01)

Reduced murine double minute-2 methylation from peripheral blood mononuclear cells correlates with enhanced oxidative stress in hepatitis b virus-related hepatocellular carcinoma
by: Jing-Wen Wang, et al.
Published: (2025-05-01)

A novel gene signature for forecasting time to next relapse in multiple sclerosis using peripheral blood mononuclear cells
by: Huimin Zhang, et al.
Published: (2025-07-01)

Cell-cycle and Apoptosis Regulators (p16INK4A, p21CIP1, α-Catenin, Survivin, and hTERT) and Morphometry-Defined MPECs Predict Metachronous Cancer Development in Colorectal Adenoma Patients
by: Kjetil Soreide, et al.
Published: (2007-01-01)

Interferon Alpha Association with Neuromyelitis Optica
by: Nasrin Asgari, et al.
Published: (2013-01-01)

Comparative efficacy and safety of pegylated interferon-alpha monotherapy vs combination therapies with entecavir or tenofovir in chronic hepatitis B patients
by: Huiqing Liang, et al.
Published: (2025-05-01)

Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in Hyperuricemia and Gout
by: Valentin NICA, et al.
Published: (2025-05-01)

Interferon-Alpha-Induced Changes in Metallothionein Expression in Liver Biopsies from Patients with Chronic Hepatitis C
by: Takeaki Nagamine, et al.
Published: (2005-01-01)

Large Intestine Histopathology of Pegylated-Interferon-Alpha Plus Ribavirin Treated Chronic Hepatitis C Patients
by: Konstantinos D. Pantazis, et al.
Published: (2008-01-01)

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients
by: Yong Xiong, et al.
Published: (2020-01-01)

Exogenous interferon-alpha and interferon-gamma increase lethality of murine inhalational anthrax.
by: Jeffrey A Gold, et al.
Published: (2007-08-01)

Interferon Gamma and Tumor Necrosis Factor Alpha Are Inflammatory Biomarkers for Major Adverse Cardiovascular Events in Patients with Peripheral Artery Disease
by: Ben Li, et al.
Published: (2025-06-01)

Type I/II Interferon in HIV-1-Infected Patients: Expression in Gut Mucosa and in Peripheral Blood Mononuclear Cells and Its Modification upon Probiotic Supplementation
by: Claudia Pinacchio, et al.
Published: (2018-01-01)

Cystic craniopharyngioma: intratumoral chemotherapy with alpha interferon
by: Patrícia Alessandra Dastoli, et al.
Published: (2011-02-01)

Secretome of peripheral blood mononuclear cells enhances wound healing.
by: Michael Mildner, et al.
Published: (2013-01-01)

DNA damage in peripheral blood mononuclear cells in patients with melanoma
by: E. V. Tsyrlina, et al.
Published: (2022-06-01)

Chronic hepatitis b with type I diabetes mellitus and autoimmune thyroiditis development during interferon alpha therapy
by: Sukran Kose, et al.
Published: (2011-07-01)

Publicly Funded, Pegylated Interferon-Alpha Treatment in British Columbia: Disparities in Treatment Patterns for People with Hepatitis C
by: Priscilla C Hsu, et al.
Published: (2008-01-01)

Interferon Alpha Induces Sustained Changes in NK Cell Responsiveness to Hepatitis B Viral Load Suppression In Vivo.
by: Upkar S Gill, et al.
Published: (2016-08-01)

Virus-host interaction mechanisms in interferon therapy for hepatitis B virus infection: recent advances
by: Jiebing Zhang, et al.
Published: (2025-06-01)

Identifying Potential New Gene Expression-Based Biomarkers in the Peripheral Blood Mononuclear Cells of Hepatitis B-Related Hepatocellular Carcinoma
by: Vahdat Poortahmasebi, et al.
Published: (2022-01-01)

B-Cell-Activating Factor Affects the Occurrence of Thyroid Autoimmunity in Chronic Hepatitis C Patients Treated with Interferon Alpha
by: Yusuke Kajiyama, et al.
Published: (2012-01-01)

Effects of interferon-alpha treatment on the incidence of hyperglycemia in chronic hepatitis C patients: a systematic review and meta-analysis.
by: Wei Zhang, et al.
Published: (2012-01-01)

Age-dependent differences in type I interferon, IL-12 and pro-inflammatory cytokine production by porcine peripheral blood mononuclear cells in response to pseudorabies virus-infected cells
by: Manon S. C. Claeys, et al.
Published: (2025-07-01)

EXPRESSION OF T-bet FACTOR IN PERIPHERAL BLOOD MONONUCLEAR CELLS IN BRONCHIAL ASTHMA
by: V. N. Mineev, et al.
Published: (2014-07-01)

THE EFFECTS OF NITROGLYCERIN ON THE PROLIFERATIVE AND MIGRATORY POTENTIAL OF PERIPHERAL BLOOD MONONUCLEAR CELLS
by: N. A. Bondarenko, et al.
Published: (2014-12-01)

Amyotrophic lateral sclerosis multiprotein biomarkers in peripheral blood mononuclear cells.
by: Giovanni Nardo, et al.
Published: (2011-01-01)