How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers

The use of network meta-analysis (NMA) in sport and exercise medicine (SEM) research continues to rise as it enables the comparison of multiple interventions that may not have been assessed in a single randomised controlled trial. NMA can then inform clinicians on potentially better interventions. D...

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Main Authors: Patrick J Owen, Daniel L Belavy, Adriani Nikolakopoulou, Tobias Saueressig, Svenja Kaczorowski
Format: Article
Language:English
Published: BMJ Publishing Group 2024-12-01
Series:BMJ Open Sport & Exercise Medicine
Online Access:https://bmjopensem.bmj.com/content/10/4/e002262.full
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author Patrick J Owen
Daniel L Belavy
Adriani Nikolakopoulou
Tobias Saueressig
Svenja Kaczorowski
author_facet Patrick J Owen
Daniel L Belavy
Adriani Nikolakopoulou
Tobias Saueressig
Svenja Kaczorowski
author_sort Patrick J Owen
collection DOAJ
description The use of network meta-analysis (NMA) in sport and exercise medicine (SEM) research continues to rise as it enables the comparison of multiple interventions that may not have been assessed in a single randomised controlled trial. NMA can then inform clinicians on potentially better interventions. Despite the increased use of NMA, we have observed that in the SEM field, a key challenge for author groups can be the assessment and reporting of key assumptions, in particular transitivity and consistency. This paper provides SEM researchers with a practical guide on how to approach the transitivity and consistency assumptions of NMA. Using a previously published NMA in the SEM field, we provide the statistical code, source data and worked examples to facilitate understanding and best practice of NMA in the particular field. We hope these resources result in improved conduct and reporting of NMA that ultimately leads to advances in the SEM field.
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issn 2055-7647
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publishDate 2024-12-01
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series BMJ Open Sport & Exercise Medicine
spelling doaj-art-e1602bc15d8b435cae4ac23a17e8819e2025-01-20T06:45:09ZengBMJ Publishing GroupBMJ Open Sport & Exercise Medicine2055-76472024-12-0110410.1136/bmjsem-2024-002262How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchersPatrick J Owen0Daniel L Belavy1Adriani Nikolakopoulou2Tobias Saueressig3Svenja Kaczorowski4Eastern Health, Melbourne, Victoria, AustraliaDepartment für Pflege-, Hebammen- und Therapiewissenschaften, Hochschule für Gesundheit, Bochum, GermanySchool of Medicine, Aristotle University of Thessaloniki, Thessalonike, Kentrikḗ Makedonía, GreecePhysio Meets Science GmbH, Heidelberg, GermanyDepartment für Pflege-, Hebammen- und Therapiewissenschaften, Hochschule für Gesundheit, Bochum, GermanyThe use of network meta-analysis (NMA) in sport and exercise medicine (SEM) research continues to rise as it enables the comparison of multiple interventions that may not have been assessed in a single randomised controlled trial. NMA can then inform clinicians on potentially better interventions. Despite the increased use of NMA, we have observed that in the SEM field, a key challenge for author groups can be the assessment and reporting of key assumptions, in particular transitivity and consistency. This paper provides SEM researchers with a practical guide on how to approach the transitivity and consistency assumptions of NMA. Using a previously published NMA in the SEM field, we provide the statistical code, source data and worked examples to facilitate understanding and best practice of NMA in the particular field. We hope these resources result in improved conduct and reporting of NMA that ultimately leads to advances in the SEM field.https://bmjopensem.bmj.com/content/10/4/e002262.full
spellingShingle Patrick J Owen
Daniel L Belavy
Adriani Nikolakopoulou
Tobias Saueressig
Svenja Kaczorowski
How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
BMJ Open Sport & Exercise Medicine
title How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
title_full How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
title_fullStr How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
title_full_unstemmed How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
title_short How to conduct and report checking transitivity and inconsistency in network-meta-analysis: a narrative review including practical worked examples, code and source data for sports and exercise medicine researchers
title_sort how to conduct and report checking transitivity and inconsistency in network meta analysis a narrative review including practical worked examples code and source data for sports and exercise medicine researchers
url https://bmjopensem.bmj.com/content/10/4/e002262.full
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