The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels

Abstract Alpha-bisabolol and camphene have demonstrated analgesic effects in inflammatory pain models by blocking Cav3.2 calcium channels. As the pain pathway overlaps with mechanisms for itch, and because Cav3.2 channels have been associated with itch in our previous work, we aimed to investigate t...

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Bibliographic Details
Main Authors: Flavia T. T. Antunes, Vinicius M. Gadotti, Gerald W. Zamponi
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Molecular Brain
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Online Access:https://doi.org/10.1186/s13041-025-01196-9
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