Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis
A lot of data suggests endocrine gland-derived vascular endothelial growth factor (EG-VEGF) to be restricted to endocrine glands and to some endocrine-dependent organs. Many evidences show that EG-VEGF stimulates angiogenesis and cell proliferation, although it is not a member of the VEGF family. At...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/3232905 |
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| author | Ana Silvia Corlan Anca Maria Cîmpean Adriana-Andreea Jitariu Eugen Melnic Marius Raica |
| author_facet | Ana Silvia Corlan Anca Maria Cîmpean Adriana-Andreea Jitariu Eugen Melnic Marius Raica |
| author_sort | Ana Silvia Corlan |
| collection | DOAJ |
| description | A lot of data suggests endocrine gland-derived vascular endothelial growth factor (EG-VEGF) to be restricted to endocrine glands and to some endocrine-dependent organs. Many evidences show that EG-VEGF stimulates angiogenesis and cell proliferation, although it is not a member of the VEGF family. At the time, a lot of data regarding the role of this growth factor in normal development are available. However, controversial results have been published in the case of pathological conditions and particularly in malignant tumors. Thus, our present paper has been focused on the role of EG-VEGF in normal tissues and various malignant tumors and their angiogenic processes. |
| format | Article |
| id | doaj-art-e114fa3af11c409cade07275f22f5088 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-e114fa3af11c409cade07275f22f50882025-02-03T01:01:03ZengWileyInternational Journal of Endocrinology1687-83371687-83452017-01-01201710.1155/2017/32329053232905Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor AngiogenesisAna Silvia Corlan0Anca Maria Cîmpean1Adriana-Andreea Jitariu2Eugen Melnic3Marius Raica4Department of Endocrinology, “Vasile Goldis” University of Arad, Arad, RomaniaDepartment of Microscopic Morphology/Histology, Angiogenesis Research Center, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Timișoara, RomaniaDepartment of Microscopic Morphology/Histology, Angiogenesis Research Center, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Timișoara, RomaniaDepartment of Pathology, “Nicolae Testemitanu” University of Medicine and Pharmacy, Chișinău, MoldovaDepartment of Microscopic Morphology/Histology, Angiogenesis Research Center, “Victor Babeș” University of Medicine and Pharmacy Timișoara, Timișoara, RomaniaA lot of data suggests endocrine gland-derived vascular endothelial growth factor (EG-VEGF) to be restricted to endocrine glands and to some endocrine-dependent organs. Many evidences show that EG-VEGF stimulates angiogenesis and cell proliferation, although it is not a member of the VEGF family. At the time, a lot of data regarding the role of this growth factor in normal development are available. However, controversial results have been published in the case of pathological conditions and particularly in malignant tumors. Thus, our present paper has been focused on the role of EG-VEGF in normal tissues and various malignant tumors and their angiogenic processes.http://dx.doi.org/10.1155/2017/3232905 |
| spellingShingle | Ana Silvia Corlan Anca Maria Cîmpean Adriana-Andreea Jitariu Eugen Melnic Marius Raica Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis International Journal of Endocrinology |
| title | Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis |
| title_full | Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis |
| title_fullStr | Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis |
| title_full_unstemmed | Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis |
| title_short | Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis |
| title_sort | endocrine gland derived vascular endothelial growth factor prokineticin 1 in cancer development and tumor angiogenesis |
| url | http://dx.doi.org/10.1155/2017/3232905 |
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