Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position

A good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl acetoacetate in the presence of ammonium fluoride. Whe...

Full description

Saved in:
Bibliographic Details
Main Authors: Davood Habibi, Mohammad Ali Zolfigol, Maliheh Safaee
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2013/495982
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850166342103072768
author Davood Habibi
Mohammad Ali Zolfigol
Maliheh Safaee
author_facet Davood Habibi
Mohammad Ali Zolfigol
Maliheh Safaee
author_sort Davood Habibi
collection DOAJ
description A good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl acetoacetate in the presence of ammonium fluoride. When phenyl isothiocyanate was used in place of phenyl isocyanate in the same condition, the reaction did not take place.
format Article
id doaj-art-e10e7f4a853c4828bbc2c8c1fc9d4cf4
institution OA Journals
issn 2090-9063
2090-9071
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Journal of Chemistry
spelling doaj-art-e10e7f4a853c4828bbc2c8c1fc9d4cf42025-08-20T02:21:29ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/495982495982Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-PositionDavood Habibi0Mohammad Ali Zolfigol1Maliheh Safaee2Department of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, IranDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, IranDepartment of Organic Chemistry, Faculty of Chemistry, Bu-Ali Sina University, Hamedan 6517838683, IranA good range of 1,4-dihydropyridines bearing a carbamate moiety on the 4-position were synthesized from the primary reaction of different hydroxyaldehydes with phenyl isocyanates and the subsequent reaction of the obtained carbamates with methyl acetoacetate in the presence of ammonium fluoride. When phenyl isothiocyanate was used in place of phenyl isocyanate in the same condition, the reaction did not take place.http://dx.doi.org/10.1155/2013/495982
spellingShingle Davood Habibi
Mohammad Ali Zolfigol
Maliheh Safaee
Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
Journal of Chemistry
title Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
title_full Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
title_fullStr Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
title_full_unstemmed Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
title_short Synthesis of 1,4-Dihydropyridines Bearing a Carbamate Moiety on the 4-Position
title_sort synthesis of 1 4 dihydropyridines bearing a carbamate moiety on the 4 position
url http://dx.doi.org/10.1155/2013/495982
work_keys_str_mv AT davoodhabibi synthesisof14dihydropyridinesbearingacarbamatemoietyonthe4position
AT mohammadalizolfigol synthesisof14dihydropyridinesbearingacarbamatemoietyonthe4position
AT malihehsafaee synthesisof14dihydropyridinesbearingacarbamatemoietyonthe4position