Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])

Abstract Objectives Epilepsy is a common chronic neurological disorder in pediatrics. Depression is an often underdetected comorbidity in childhood epilepsy. This study aimed to adapt the Neurological Disorders Depression Inventory‐Epilepsy for Youth (NDDI‐E‐Y) to the Indonesian language and populat...

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Main Authors: Setyo Handryastuti, Tjhin Wiguna, Novie Amelia Chozie, Bernie Endyarni Medise, Wahyuni Indawati, Cut Nurul Hafifah, Widdy Winarta
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Epilepsia Open
Subjects:
Online Access:https://doi.org/10.1002/epi4.13052
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author Setyo Handryastuti
Tjhin Wiguna
Novie Amelia Chozie
Bernie Endyarni Medise
Wahyuni Indawati
Cut Nurul Hafifah
Widdy Winarta
author_facet Setyo Handryastuti
Tjhin Wiguna
Novie Amelia Chozie
Bernie Endyarni Medise
Wahyuni Indawati
Cut Nurul Hafifah
Widdy Winarta
author_sort Setyo Handryastuti
collection DOAJ
description Abstract Objectives Epilepsy is a common chronic neurological disorder in pediatrics. Depression is an often underdetected comorbidity in childhood epilepsy. This study aimed to adapt the Neurological Disorders Depression Inventory‐Epilepsy for Youth (NDDI‐E‐Y) to the Indonesian language and population, as well as to validate the Indonesian version of NDDI‐E‐Y (NDDI‐E‐Y[ID]). Methods This three‐stage study comprised instrument translation, cultural verification, and content validity testing (first stage), pilot testing (second stage), followed by concurrent validity and reliability testing (third stage) of the NDDI‐E‐Y(ID). Validation was done against the Centre for Epidemiologic Studies Depression Scale – Revised (CESD‐R). Content validity, assessed by six experts, was quantified using the content validity index for items (I‐CVI) and scale (S‐CVI). Participants were adolescents aged 12–17 years diagnosed with any type of epilepsy who completed both instruments. Concurrent validity was evaluated using Spearman's correlation and reliability was measured using Cronbach's alpha. Results The first stage produced a culturally appropriate NDDI‐E‐Y(ID). Thirty healthy adolescents and 10 adolescents with epilepsy participated in the second stage. In the third stage, another group of 30 adolescents with epilepsy took part. We obtained I‐CVI and S‐CVI values averaging 1. The NDDI‐E‐Y(ID) showed a positive and significant correlation with CESD‐R (Spearman's rho = 0.671, p < 0.001). A Cronbach's alpha of 0.928 reflected a high internal consistency. Significance Based on the results, the NDDI‐E‐Y(ID) was found to be a valid and reliable screening instrument for detecting depression in youth with epilepsy. Plain Language Summary Depression is an under‐recognized problem in youth with epilepsy. Currently available depression screening tools are in English, making it less suitable for detection purposes in Indonesia. This study developed and validated the Indonesian version of the NDDI‐E‐Y, a depression screening tool for youth with epilepsy.
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spelling doaj-art-e106096a5de54bc1bef53d7febec0f172025-08-20T02:33:46ZengWileyEpilepsia Open2470-92392024-12-01962342235210.1002/epi4.13052Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])Setyo Handryastuti0Tjhin Wiguna1Novie Amelia Chozie2Bernie Endyarni Medise3Wahyuni Indawati4Cut Nurul Hafifah5Widdy Winarta6Department of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Psychiatry Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaDepartment of Child Health Faculty of Medicine Universitas Indonesia – Cipto Mangunkusumo General Hospital Jakarta IndonesiaAbstract Objectives Epilepsy is a common chronic neurological disorder in pediatrics. Depression is an often underdetected comorbidity in childhood epilepsy. This study aimed to adapt the Neurological Disorders Depression Inventory‐Epilepsy for Youth (NDDI‐E‐Y) to the Indonesian language and population, as well as to validate the Indonesian version of NDDI‐E‐Y (NDDI‐E‐Y[ID]). Methods This three‐stage study comprised instrument translation, cultural verification, and content validity testing (first stage), pilot testing (second stage), followed by concurrent validity and reliability testing (third stage) of the NDDI‐E‐Y(ID). Validation was done against the Centre for Epidemiologic Studies Depression Scale – Revised (CESD‐R). Content validity, assessed by six experts, was quantified using the content validity index for items (I‐CVI) and scale (S‐CVI). Participants were adolescents aged 12–17 years diagnosed with any type of epilepsy who completed both instruments. Concurrent validity was evaluated using Spearman's correlation and reliability was measured using Cronbach's alpha. Results The first stage produced a culturally appropriate NDDI‐E‐Y(ID). Thirty healthy adolescents and 10 adolescents with epilepsy participated in the second stage. In the third stage, another group of 30 adolescents with epilepsy took part. We obtained I‐CVI and S‐CVI values averaging 1. The NDDI‐E‐Y(ID) showed a positive and significant correlation with CESD‐R (Spearman's rho = 0.671, p < 0.001). A Cronbach's alpha of 0.928 reflected a high internal consistency. Significance Based on the results, the NDDI‐E‐Y(ID) was found to be a valid and reliable screening instrument for detecting depression in youth with epilepsy. Plain Language Summary Depression is an under‐recognized problem in youth with epilepsy. Currently available depression screening tools are in English, making it less suitable for detection purposes in Indonesia. This study developed and validated the Indonesian version of the NDDI‐E‐Y, a depression screening tool for youth with epilepsy.https://doi.org/10.1002/epi4.13052concurrent validitycontent validitydepressionepilepsyreliabilityyouth
spellingShingle Setyo Handryastuti
Tjhin Wiguna
Novie Amelia Chozie
Bernie Endyarni Medise
Wahyuni Indawati
Cut Nurul Hafifah
Widdy Winarta
Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
Epilepsia Open
concurrent validity
content validity
depression
epilepsy
reliability
youth
title Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
title_full Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
title_fullStr Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
title_full_unstemmed Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
title_short Evaluating depression in Indonesian adolescents with epilepsy: Comprehensive validation and reliability assessment of the neurological disorders depression inventory‐epilepsy for youth Indonesian version (NDDI‐E‐Y[ID])
title_sort evaluating depression in indonesian adolescents with epilepsy comprehensive validation and reliability assessment of the neurological disorders depression inventory epilepsy for youth indonesian version nddi e y id
topic concurrent validity
content validity
depression
epilepsy
reliability
youth
url https://doi.org/10.1002/epi4.13052
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