Leveraging AI to explore structural contexts of post-translational modifications in drug binding
Abstract Post-translational modifications (PTMs) play a crucial role in allowing cells to expand the functionality of their proteins and adaptively regulate their signaling pathways. Defects in PTMs have been linked to numerous developmental disorders and human diseases, including cancer, diabetes,...
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| Main Authors: | Kirill E. Medvedev, R. Dustin Schaeffer, Nick V. Grishin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-05-01
|
| Series: | Journal of Cheminformatics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13321-025-01019-y |
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