Blockade of Alternative Complement Pathway in Dense Deposit Disease

A patient aged 17 with dense deposit disease associated with complement activation, circulating C3 Nef, and Factor H mutation presented with nephrotic syndrome and hypertension. Steroid therapy, plasma exchange, and rituximab failed to improve proteinuria and hypertension despite a normalization of...

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Bibliographic Details
Main Authors: Aurore Berthe-Aucejo, Mathieu Sacquépée, Marc Fila, Michel Peuchmaur, Emilia Perrier-Cornet, Véronique Frémeaux-Bacchi, Georges Deschênes
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2014/201568
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