Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies

In recent years, the field of wearable sensors has undergone significant evolution, emerging as a pivotal topic of research due to the capacity of such sensors to gather physiological data during various human activities. Transitioning from basic fitness trackers, these sensors are continuously bein...

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Main Authors: Mahmoud Abdelwahab Fathy, Philippe Bühlmann
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/15/1/51
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author Mahmoud Abdelwahab Fathy
Philippe Bühlmann
author_facet Mahmoud Abdelwahab Fathy
Philippe Bühlmann
author_sort Mahmoud Abdelwahab Fathy
collection DOAJ
description In recent years, the field of wearable sensors has undergone significant evolution, emerging as a pivotal topic of research due to the capacity of such sensors to gather physiological data during various human activities. Transitioning from basic fitness trackers, these sensors are continuously being improved, with the ultimate objective to make compact, sophisticated, highly integrated, and adaptable multi-functional devices that seamlessly connect to clothing or the body, and continuously monitor bodily signals without impeding the wearer’s comfort or well-being. Potentiometric sensors, leveraging a range of different solid contact materials, have emerged as a preferred choice for wearable chemical or biological sensors. Nanomaterials play a pivotal role, offering unique properties, such as high conductivity and surface-to-volume ratios. This article provides a review of recent advancements in wearable potentiometric sensors utilizing various solid contacts, with a particular emphasis on nanomaterials. These sensors are employed for precise ion concentration determinations, notably sodium, potassium, calcium, magnesium, ammonium, and chloride, in human biological fluids. This review highlights two primary applications, that is, (1) the enhancement of athletic performance by continuous monitoring of ion levels in sweat to gauge the athlete’s health status, and (2) the facilitation of clinical diagnosis and preventive healthcare by monitoring the health status of patients, in particular to detect early signs of dehydration, fatigue, and muscle spasms.
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spelling doaj-art-e0b9145a249848f5bddf081b65989f782025-01-24T13:25:34ZengMDPI AGBiosensors2079-63742025-01-011515110.3390/bios15010051Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable TechnologiesMahmoud Abdelwahab Fathy0Philippe Bühlmann1Department of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN 55455, USADepartment of Chemistry, University of Minnesota, 207 Pleasant St. SE, Minneapolis, MN 55455, USAIn recent years, the field of wearable sensors has undergone significant evolution, emerging as a pivotal topic of research due to the capacity of such sensors to gather physiological data during various human activities. Transitioning from basic fitness trackers, these sensors are continuously being improved, with the ultimate objective to make compact, sophisticated, highly integrated, and adaptable multi-functional devices that seamlessly connect to clothing or the body, and continuously monitor bodily signals without impeding the wearer’s comfort or well-being. Potentiometric sensors, leveraging a range of different solid contact materials, have emerged as a preferred choice for wearable chemical or biological sensors. Nanomaterials play a pivotal role, offering unique properties, such as high conductivity and surface-to-volume ratios. This article provides a review of recent advancements in wearable potentiometric sensors utilizing various solid contacts, with a particular emphasis on nanomaterials. These sensors are employed for precise ion concentration determinations, notably sodium, potassium, calcium, magnesium, ammonium, and chloride, in human biological fluids. This review highlights two primary applications, that is, (1) the enhancement of athletic performance by continuous monitoring of ion levels in sweat to gauge the athlete’s health status, and (2) the facilitation of clinical diagnosis and preventive healthcare by monitoring the health status of patients, in particular to detect early signs of dehydration, fatigue, and muscle spasms.https://www.mdpi.com/2079-6374/15/1/51wearable sensorspotentiometrysweat analysissport performanceclinical diagnosisionophore
spellingShingle Mahmoud Abdelwahab Fathy
Philippe Bühlmann
Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
Biosensors
wearable sensors
potentiometry
sweat analysis
sport performance
clinical diagnosis
ionophore
title Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
title_full Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
title_fullStr Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
title_full_unstemmed Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
title_short Next-Generation Potentiometric Sensors: A Review of Flexible and Wearable Technologies
title_sort next generation potentiometric sensors a review of flexible and wearable technologies
topic wearable sensors
potentiometry
sweat analysis
sport performance
clinical diagnosis
ionophore
url https://www.mdpi.com/2079-6374/15/1/51
work_keys_str_mv AT mahmoudabdelwahabfathy nextgenerationpotentiometricsensorsareviewofflexibleandwearabletechnologies
AT philippebuhlmann nextgenerationpotentiometricsensorsareviewofflexibleandwearabletechnologies