Dynamic multi-omics and mechanistic modeling approach uncovers novel mechanisms of kidney fibrosis progression
Abstract Kidney fibrosis, characterized by excessive extracellular matrix deposition, is a progressive disease that, despite affecting 10% of the population, lacks specific treatments and suitable biomarkers. This study presents a comprehensive, time-resolved multi-omics analysis of kidney fibrosis...
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| Main Authors: | Nadine Tuechler, Mira Lea Burtscher, Martin Garrido-Rodriguez, Muzamil Majid Khan, Dénes Türei, Christian Tischer, Sarah Kaspar, Jennifer Jasmin Schwarz, Frank Stein, Mandy Rettel, Rafael Kramann, Mikhail M Savitski, Julio Saez-Rodriguez, Rainer Pepperkok |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2025-06-01
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| Series: | Molecular Systems Biology |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s44320-025-00116-2 |
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