Synergistic effects of Aurora A and AKT inhibitors combined with radiation in colon cancer cells
Abstract Purpose This study aimed to investigate the synergistic effects of combining Aurora A and AKT inhibitors with radiation therapy on colon cancer cells and to elucidate the underlying mechanisms. Methods: Human colon cancer cell lines HCT-15 and HCT-116 were treated with Alisertib (Aurora A i...
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| Main Authors: | Qiuxia Peng, Wei Zhou, Jie Li, Danqing Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-05-01
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| Series: | Discover Oncology |
| Online Access: | https://doi.org/10.1007/s12672-025-02562-8 |
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