Synergistic effects of Aurora A and AKT inhibitors combined with radiation in colon cancer cells

Abstract Purpose This study aimed to investigate the synergistic effects of combining Aurora A and AKT inhibitors with radiation therapy on colon cancer cells and to elucidate the underlying mechanisms. Methods: Human colon cancer cell lines HCT-15 and HCT-116 were treated with Alisertib (Aurora A i...

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Bibliographic Details
Main Authors: Qiuxia Peng, Wei Zhou, Jie Li, Danqing Liu
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Online Access:https://doi.org/10.1007/s12672-025-02562-8
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