COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome
The coronavirus disease-2019 (COVID-19) is usually less severe and less prevalent in the pediatric population. Children with preexisting conditions such as neuromuscular impairments and chronic lung disease are more susceptible to COVID-19 and may incur several complications with a poor outcome. We...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2021-01-01
|
| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2021/5862444 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832560631727783936 |
|---|---|
| author | Rafat Mosalli Amirah Al Matrafi Mohammed A. Ghazi Gamal A. Aboumousatafa Bosco Paes |
| author_facet | Rafat Mosalli Amirah Al Matrafi Mohammed A. Ghazi Gamal A. Aboumousatafa Bosco Paes |
| author_sort | Rafat Mosalli |
| collection | DOAJ |
| description | The coronavirus disease-2019 (COVID-19) is usually less severe and less prevalent in the pediatric population. Children with preexisting conditions such as neuromuscular impairments and chronic lung disease are more susceptible to COVID-19 and may incur several complications with a poor outcome. We present a case report of a 3-year-old-female with generalized hypotonia and respiratory failure due to spinal muscular atrophy who tested positive for COVID-19 and developed multisystem inflammatory syndrome that was treated with intravenous immunoglobulin and tocilizumab and subsequently died. The report highlights the importance of close surveillance, the use of protective measures during hospital visits, early testing, and diagnosis of COVID-19 in children with neurological disorders. |
| format | Article |
| id | doaj-art-e0a856dc5c5242d3b3870ac236de037b |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-e0a856dc5c5242d3b3870ac236de037b2025-02-03T01:27:06ZengWileyCase Reports in Pediatrics2090-68032090-68112021-01-01202110.1155/2021/58624445862444COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory SyndromeRafat Mosalli0Amirah Al Matrafi1Mohammed A. Ghazi2Gamal A. Aboumousatafa3Bosco Paes4Department of Pediatrics, Umm Al-Qura University, Mecca, Saudi ArabiaCollege of Medicine, Umm Al-Qura University, Mecca, Saudi ArabiaDepartment of Pediatrics, International Extended Care Center, Jeddah, Saudi ArabiaDepartment of Pediatrics, International Extended Care Center, Jeddah, Saudi ArabiaDepartment of Pediatrics (Neonatal Division), McMaster University, Hamilton, ON, CanadaThe coronavirus disease-2019 (COVID-19) is usually less severe and less prevalent in the pediatric population. Children with preexisting conditions such as neuromuscular impairments and chronic lung disease are more susceptible to COVID-19 and may incur several complications with a poor outcome. We present a case report of a 3-year-old-female with generalized hypotonia and respiratory failure due to spinal muscular atrophy who tested positive for COVID-19 and developed multisystem inflammatory syndrome that was treated with intravenous immunoglobulin and tocilizumab and subsequently died. The report highlights the importance of close surveillance, the use of protective measures during hospital visits, early testing, and diagnosis of COVID-19 in children with neurological disorders.http://dx.doi.org/10.1155/2021/5862444 |
| spellingShingle | Rafat Mosalli Amirah Al Matrafi Mohammed A. Ghazi Gamal A. Aboumousatafa Bosco Paes COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome Case Reports in Pediatrics |
| title | COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome |
| title_full | COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome |
| title_fullStr | COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome |
| title_full_unstemmed | COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome |
| title_short | COVID-19 Infection in Spinal Muscular Atrophy Associated with Multisystem Inflammatory Syndrome |
| title_sort | covid 19 infection in spinal muscular atrophy associated with multisystem inflammatory syndrome |
| url | http://dx.doi.org/10.1155/2021/5862444 |
| work_keys_str_mv | AT rafatmosalli covid19infectioninspinalmuscularatrophyassociatedwithmultisysteminflammatorysyndrome AT amirahalmatrafi covid19infectioninspinalmuscularatrophyassociatedwithmultisysteminflammatorysyndrome AT mohammedaghazi covid19infectioninspinalmuscularatrophyassociatedwithmultisysteminflammatorysyndrome AT gamalaaboumousatafa covid19infectioninspinalmuscularatrophyassociatedwithmultisysteminflammatorysyndrome AT boscopaes covid19infectioninspinalmuscularatrophyassociatedwithmultisysteminflammatorysyndrome |