Multiscale computational evaluation of Vitex trifolia phytochemicals as VEGFR2 inhibitors for targeted breast cancer therapy.

Breast cancer (BC), the second most common cancer, is a genetically heterogeneous disease driven by angiogenesis, cell growth, metastasis, and oxidative stress. VEGFR2, a key angiogenesis regulator, presents a potential target for inhibiting the angiogenic process essential for tumor growth. The pre...

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Main Authors: Arooj Fatima, Muhammad Umer Khan, Saooda Ibrahim, Iqra Khurram, Qasim Ammar, Raima Rehman, Alaa S Alhegaili, Raghad S Alhejaili, Nawal Alsubaie, Muhammad Ikram Ullah
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0325255
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