Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation

Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis). We describe the case of a 48 years-old woman with axonal neuropathy associated with prot...

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Bibliographic Details
Main Authors: Orlando G. Povoas Barsottini, Adriano Arantes, Daniel Sigulem, José Mauro Kutner, Andreza Alice Feitosa Ribeiro, Luiz A. Moura, Nelson Hamerschlak
Format: Article
Language:English
Published: Thieme Revinter Publicações 2004-09-01
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2004000400030&tlng=en
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Summary:Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis). We describe the case of a 48 years-old woman with axonal neuropathy associated with proteinuria, whose final investigation resulted in diagnosis of primary amyloidosis (AL). She was submitted to autologous bone marrow transplantation. We discuss some aspects related to diagnosis of neuropathy and current treatment of AL.
ISSN:1678-4227