Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication.

Longitudinal changes in total brain volume in schizophrenia: relation to symptom severity, cognition and antipsychotic medication.

Studies show evidence of longitudinal brain volume decreases in schizophrenia. We studied brain volume changes and their relation to symptom severity, level of function, cognition, and antipsychotic medication in participants with schizophrenia and control participants from a general population base...

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Main Authors: Juha Veijola, Joyce Y Guo, Jani S Moilanen, Erika Jääskeläinen, Jouko Miettunen, Merja Kyllönen, Marianne Haapea, Sanna Huhtaniska, Antti Alaräisänen, Pirjo Mäki, Vesa Kiviniemi, Juha Nikkinen, Tuomo Starck, Jukka J Remes, Päivikki Tanskanen, Osmo Tervonen, Alle-Meije Wink, Angie Kehagia, John Suckling, Hiroyuki Kobayashi, Jennifer H Barnett, Anna Barnes, Hannu J Koponen, Peter B Jones, Matti Isohanni, Graham K Murray
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0101689
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