Synthesis and Characterization of Some New Benzimidazole Derivatives

In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesi...

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Main Author: Baghdad Science Journal
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2016-03-01
Series:مجلة بغداد للعلوم
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Online Access:http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145
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author Baghdad Science Journal
author_facet Baghdad Science Journal
author_sort Baghdad Science Journal
collection DOAJ
description In this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra.
format Article
id doaj-art-e07027e17f804eee8385ff4ada3f9ff3
institution Kabale University
issn 2078-8665
2411-7986
language English
publishDate 2016-03-01
publisher University of Baghdad, College of Science for Women
record_format Article
series مجلة بغداد للعلوم
spelling doaj-art-e07027e17f804eee8385ff4ada3f9ff32025-08-20T03:39:25ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862016-03-0113110.21123/bsj.13.1.82-88Synthesis and Characterization of Some New Benzimidazole DerivativesBaghdad Science JournalIn this paper the new starting material 2-(5-chloro-1H-benzo[d]imidazole-2-yl) aniline (1) was synthesized by the condensation reaction of 4-chloro-o-phenylenediamine and anthranilic acid .The new Mannich base derivatives were synthesized using formaldehyde and different secondary amines to synthesize a new set of benzimidazole derivatives(2-5). Also, the new Schiff-base derivatives (6-10) were synthesized from the reaction of compound (1) with various aromatic aldehydes and the closure-ring was done successfully using mercapto acetic acid to get the new thiazolidine derivatives(11-12).These new compounds were characterized using some physical techniques like:FT-IR Spectra and 1HNMR Spectra.http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145"Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
spellingShingle Baghdad Science Journal
Synthesis and Characterization of Some New Benzimidazole Derivatives
مجلة بغداد للعلوم
"Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
title Synthesis and Characterization of Some New Benzimidazole Derivatives
title_full Synthesis and Characterization of Some New Benzimidazole Derivatives
title_fullStr Synthesis and Characterization of Some New Benzimidazole Derivatives
title_full_unstemmed Synthesis and Characterization of Some New Benzimidazole Derivatives
title_short Synthesis and Characterization of Some New Benzimidazole Derivatives
title_sort synthesis and characterization of some new benzimidazole derivatives
topic "Benzimidazole, Mannich bases, Schiff’s bases, Thiazolidine"
url http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/2145
work_keys_str_mv AT baghdadsciencejournal synthesisandcharacterizationofsomenewbenzimidazolederivatives