Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients
Background: For stage I–II colon cancer a significant number (5–25%) of patients has recurrent disease within 5 years. There is need to identify these high-risk patients as they might benefit from additional treatment.
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2009-01-01
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| Series: | Cellular Oncology |
| Online Access: | http://dx.doi.org/10.3233/CLO-2009-0478 |
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| _version_ | 1832549477814108160 |
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| author | Wilma E. Mesker Gerrit-Jan Liefers Jan M. C. Junggeburt Gabi W. van Pelt Paola Alberici Peter J. K. Kuppen Noel F. Miranda Karin A. M. van Leeuwen Hans Morreau Karoly Szuhai Rob A. E. M. Tollenaar Hans J. Tanke |
| author_facet | Wilma E. Mesker Gerrit-Jan Liefers Jan M. C. Junggeburt Gabi W. van Pelt Paola Alberici Peter J. K. Kuppen Noel F. Miranda Karin A. M. van Leeuwen Hans Morreau Karoly Szuhai Rob A. E. M. Tollenaar Hans J. Tanke |
| author_sort | Wilma E. Mesker |
| collection | DOAJ |
| description | Background: For stage I–II colon cancer a significant number (5–25%) of patients has recurrent disease within 5 years. There is need to identify these high-risk patients as they might benefit from additional treatment. |
| format | Article |
| id | doaj-art-e069bfb964f541919fccf088d96efb12 |
| institution | Kabale University |
| issn | 1570-5870 1875-8606 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cellular Oncology |
| spelling | doaj-art-e069bfb964f541919fccf088d96efb122025-02-03T06:11:14ZengWileyCellular Oncology1570-58701875-86062009-01-0131316917810.3233/CLO-2009-0478Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer PatientsWilma E. Mesker0Gerrit-Jan Liefers1Jan M. C. Junggeburt2Gabi W. van Pelt3Paola Alberici4Peter J. K. Kuppen5Noel F. Miranda6Karin A. M. van Leeuwen7Hans Morreau8Karoly Szuhai9Rob A. E. M. Tollenaar10Hans J. Tanke11Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pathology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Pathology, Rijnland Hospital, Leiderdorp, The NetherlandsDepartment of Pathology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Surgery, Leiden University Medical Center, Leiden, The NetherlandsDepartment of Molecular Cell Biology, Leiden University Medical Center, Leiden, The NetherlandsBackground: For stage I–II colon cancer a significant number (5–25%) of patients has recurrent disease within 5 years. There is need to identify these high-risk patients as they might benefit from additional treatment.http://dx.doi.org/10.3233/CLO-2009-0478 |
| spellingShingle | Wilma E. Mesker Gerrit-Jan Liefers Jan M. C. Junggeburt Gabi W. van Pelt Paola Alberici Peter J. K. Kuppen Noel F. Miranda Karin A. M. van Leeuwen Hans Morreau Karoly Szuhai Rob A. E. M. Tollenaar Hans J. Tanke Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients Cellular Oncology |
| title | Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients |
| title_full | Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients |
| title_fullStr | Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients |
| title_full_unstemmed | Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients |
| title_short | Presence of a High Amount of Stroma and Downregulation of SMAD4 Predict for Worse Survival for Stage I–II Colon Cancer Patients |
| title_sort | presence of a high amount of stroma and downregulation of smad4 predict for worse survival for stage i ii colon cancer patients |
| url | http://dx.doi.org/10.3233/CLO-2009-0478 |
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