Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation

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Main Author: Bin Yu
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Acta Pharmaceutica Sinica B
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525001984
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author Bin Yu
author_facet Bin Yu
author_sort Bin Yu
collection DOAJ
format Article
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institution OA Journals
issn 2211-3835
language English
publishDate 2025-04-01
publisher Elsevier
record_format Article
series Acta Pharmaceutica Sinica B
spelling doaj-art-e055ef25b0dc4970bbfdbbdb51aad5bb2025-08-20T02:28:37ZengElsevierActa Pharmaceutica Sinica B2211-38352025-04-011542293229410.1016/j.apsb.2025.03.044Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradationBin Yu0College of Chemistry, Pingyuan Laboratory, Zhengzhou University, Zhengzhou 450001, China; Tianjian Laboratory of Advanced Biomedical Sciences, Institute of Advanced Biomedical Sciences, Zhengzhou University, Zhengzhou 450001, China; Corresponding author.http://www.sciencedirect.com/science/article/pii/S2211383525001984
spellingShingle Bin Yu
Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
Acta Pharmaceutica Sinica B
title Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
title_full Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
title_fullStr Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
title_full_unstemmed Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
title_short Leveraging glypican-3 (GPC3)-mediated lysosome-targeting chimeras (GLTACs) for targeted membrane protein degradation
title_sort leveraging glypican 3 gpc3 mediated lysosome targeting chimeras gltacs for targeted membrane protein degradation
url http://www.sciencedirect.com/science/article/pii/S2211383525001984
work_keys_str_mv AT binyu leveragingglypican3gpc3mediatedlysosometargetingchimerasgltacsfortargetedmembraneproteindegradation