Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries
Abstract The relationship between ramp lesion (RL), tibial slope (TS), and meniscal slope (MS) remains inadequately explored. This study aims to investigate whether TS and MS are predictive factors for anterior cruciate ligament (ACL) injuries associated with RL, and to evaluate the performance of T...
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Nature Portfolio
2025-05-01
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| Online Access: | https://doi.org/10.1038/s41598-025-99592-7 |
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| author | Xiaotan Wang Kun Liu Le Yu Jiushan Yang Lizhong Jing Steven Duhig |
| author_facet | Xiaotan Wang Kun Liu Le Yu Jiushan Yang Lizhong Jing Steven Duhig |
| author_sort | Xiaotan Wang |
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| description | Abstract The relationship between ramp lesion (RL), tibial slope (TS), and meniscal slope (MS) remains inadequately explored. This study aims to investigate whether TS and MS are predictive factors for anterior cruciate ligament (ACL) injuries associated with RL, and to evaluate the performance of TS and MS in predicting RL, including determining optimal cut-off values. A retrospective cohort study was conducted on 253 patients who underwent ACL reconstruction. Magnetic resonance imaging was used to measure TS and MS on tibial plateaus. Logistic regression analyses determined associations between TS, MS, and RL. Receiver operating characteristic (ROC) curves evaluated predictive performance and cut-off values. A total of 65 cases (25.7%) were found to have RL. Significant differences in causes of injury, medial TS (MTS), medial MS (MMS), and bone bruises were observed between groups. In the unadjusted model and adjusted models, they showed significant (P < 0.001) associations for MTS (1.73–1.75) and MMS (OR range = 2.14–2.24). The AUC for MTS was 0.72 (95% CI 0.65–0.79, P < 0.001) with a cut-off value of 6.73°, for MMS was 0.80 (95% CI 0.74–0.86, P < 0.001) with a cut-off value of 4.03°, indicating good predictive performance. Larger MTS and MMS are significant predictive factors for RL in patients with ACL injury. Clinicians should closely monitor ACL injury patients with elevated MTS or MMS. Utilizing MTS or MMS as a predictive parameter shows promise for the identification of RL. |
| format | Article |
| id | doaj-art-e02f97d427d84de9a4a8aec5aa53ebf6 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Nature Portfolio |
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| spelling | doaj-art-e02f97d427d84de9a4a8aec5aa53ebf62025-08-20T03:52:24ZengNature PortfolioScientific Reports2045-23222025-05-0115111010.1038/s41598-025-99592-7Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuriesXiaotan Wang0Kun Liu1Le Yu2Jiushan Yang3Lizhong Jing4Steven Duhig5Department of Sports Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineThe Second Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Sports Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Sports Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineDepartment of Sports Medicine, Affiliated Hospital of Shandong University of Traditional Chinese MedicineSchool of Health Sciences and Social Work, Griffith UniversityAbstract The relationship between ramp lesion (RL), tibial slope (TS), and meniscal slope (MS) remains inadequately explored. This study aims to investigate whether TS and MS are predictive factors for anterior cruciate ligament (ACL) injuries associated with RL, and to evaluate the performance of TS and MS in predicting RL, including determining optimal cut-off values. A retrospective cohort study was conducted on 253 patients who underwent ACL reconstruction. Magnetic resonance imaging was used to measure TS and MS on tibial plateaus. Logistic regression analyses determined associations between TS, MS, and RL. Receiver operating characteristic (ROC) curves evaluated predictive performance and cut-off values. A total of 65 cases (25.7%) were found to have RL. Significant differences in causes of injury, medial TS (MTS), medial MS (MMS), and bone bruises were observed between groups. In the unadjusted model and adjusted models, they showed significant (P < 0.001) associations for MTS (1.73–1.75) and MMS (OR range = 2.14–2.24). The AUC for MTS was 0.72 (95% CI 0.65–0.79, P < 0.001) with a cut-off value of 6.73°, for MMS was 0.80 (95% CI 0.74–0.86, P < 0.001) with a cut-off value of 4.03°, indicating good predictive performance. Larger MTS and MMS are significant predictive factors for RL in patients with ACL injury. Clinicians should closely monitor ACL injury patients with elevated MTS or MMS. Utilizing MTS or MMS as a predictive parameter shows promise for the identification of RL.https://doi.org/10.1038/s41598-025-99592-7Magnetic resonance imagingKnee jointCohort studiesDiagnostic techniques and procedures |
| spellingShingle | Xiaotan Wang Kun Liu Le Yu Jiushan Yang Lizhong Jing Steven Duhig Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries Scientific Reports Magnetic resonance imaging Knee joint Cohort studies Diagnostic techniques and procedures |
| title | Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| title_full | Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| title_fullStr | Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| title_full_unstemmed | Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| title_short | Steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| title_sort | steeper tibial and meniscal slopes as predictive factors for ramp lesions in anterior cruciate ligament injuries |
| topic | Magnetic resonance imaging Knee joint Cohort studies Diagnostic techniques and procedures |
| url | https://doi.org/10.1038/s41598-025-99592-7 |
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