Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience
Background. There is not enough evidence about clinical behavior of bladder cancer in younger patients. Objective. We aimed to evaluate the clinical characteristics and prognosis of bladder urothelial carcinoma patients under the age of 40 years. Methods. Medical records of patients listed in our ca...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Scientifica |
| Online Access: | http://dx.doi.org/10.1155/2016/6792484 |
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| author | Volkan Sen Ozan Bozkurt Omer Demir Ahmet Adil Esen Ugur Mungan Guven Aslan Aykut Kefi Ilhan Celebi |
| author_facet | Volkan Sen Ozan Bozkurt Omer Demir Ahmet Adil Esen Ugur Mungan Guven Aslan Aykut Kefi Ilhan Celebi |
| author_sort | Volkan Sen |
| collection | DOAJ |
| description | Background. There is not enough evidence about clinical behavior of bladder cancer in younger patients. Objective. We aimed to evaluate the clinical characteristics and prognosis of bladder urothelial carcinoma patients under the age of 40 years. Methods. Medical records of patients listed in our cancer database were retrospectively reviewed. A total of 40 patients who were initially diagnosed with bladder urothelial carcinoma at the age less than 40 years were included in the study. Patients’ records were reviewed for recurrence and progression rates, demographic data, medical history, and treatment modalities. Results. Pathological results revealed 33 (82.5%) Ta low-grade, 6 (15%) T1 high-grade, and 1 (2.5%) T2 high-grade urothelial carcinomas. Recurrence was detected in 14/39 (35.9%) patients but progression was not observed in any patients. The mean age of recurrent patients was significantly higher than nonrecurrent patients (34.8 versus 28.5 years; p<0.05). Besides, recurrence was detected in only 1 patient with the age under 30 years (6.2%) and 13 patients (54.1%) between 30 and 40 years old, respectively (p<0.05). Conclusion. Bladder urothelial carcinoma diagnosed at young age tends to be a low pathologic stage, with relatively low rate of recurrence and progression. |
| format | Article |
| id | doaj-art-e02efd8c99174ebcb22dfba6afda6e24 |
| institution | Kabale University |
| issn | 2090-908X |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Scientifica |
| spelling | doaj-art-e02efd8c99174ebcb22dfba6afda6e242025-02-03T01:12:02ZengWileyScientifica2090-908X2016-01-01201610.1155/2016/67924846792484Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center ExperienceVolkan Sen0Ozan Bozkurt1Omer Demir2Ahmet Adil Esen3Ugur Mungan4Guven Aslan5Aykut Kefi6Ilhan Celebi7Department of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyDepartment of Urology, Dokuz Eylul University School of Medicine, 35330 Izmir, TurkeyBackground. There is not enough evidence about clinical behavior of bladder cancer in younger patients. Objective. We aimed to evaluate the clinical characteristics and prognosis of bladder urothelial carcinoma patients under the age of 40 years. Methods. Medical records of patients listed in our cancer database were retrospectively reviewed. A total of 40 patients who were initially diagnosed with bladder urothelial carcinoma at the age less than 40 years were included in the study. Patients’ records were reviewed for recurrence and progression rates, demographic data, medical history, and treatment modalities. Results. Pathological results revealed 33 (82.5%) Ta low-grade, 6 (15%) T1 high-grade, and 1 (2.5%) T2 high-grade urothelial carcinomas. Recurrence was detected in 14/39 (35.9%) patients but progression was not observed in any patients. The mean age of recurrent patients was significantly higher than nonrecurrent patients (34.8 versus 28.5 years; p<0.05). Besides, recurrence was detected in only 1 patient with the age under 30 years (6.2%) and 13 patients (54.1%) between 30 and 40 years old, respectively (p<0.05). Conclusion. Bladder urothelial carcinoma diagnosed at young age tends to be a low pathologic stage, with relatively low rate of recurrence and progression.http://dx.doi.org/10.1155/2016/6792484 |
| spellingShingle | Volkan Sen Ozan Bozkurt Omer Demir Ahmet Adil Esen Ugur Mungan Guven Aslan Aykut Kefi Ilhan Celebi Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience Scientifica |
| title | Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience |
| title_full | Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience |
| title_fullStr | Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience |
| title_full_unstemmed | Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience |
| title_short | Clinical Behavior of Bladder Urothelial Carcinoma in Young Patients: A Single Center Experience |
| title_sort | clinical behavior of bladder urothelial carcinoma in young patients a single center experience |
| url | http://dx.doi.org/10.1155/2016/6792484 |
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