Review of the Predictive Value of Biomarkers in Sepsis Mortality

Sepsis is a leading cause of mortality among severely ill individuals, primarily due to its potential to induce fatal organ dysfunction. For clinicians, it is vital to have appropriate indicators, including the physiological status and personal experiences of patients with sepsis, to monitor the con...

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Main Authors: Nai Zhang, Yujuan Liu, Chuang Yang, Xinai Li
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Emergency Medicine International
Online Access:http://dx.doi.org/10.1155/2024/2715606
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author Nai Zhang
Yujuan Liu
Chuang Yang
Xinai Li
author_facet Nai Zhang
Yujuan Liu
Chuang Yang
Xinai Li
author_sort Nai Zhang
collection DOAJ
description Sepsis is a leading cause of mortality among severely ill individuals, primarily due to its potential to induce fatal organ dysfunction. For clinicians, it is vital to have appropriate indicators, including the physiological status and personal experiences of patients with sepsis, to monitor the condition and assess prognosis. This approach aids in preventing the worsening of the illness and reduces mortality. Recent guidelines for sepsis focus on improving patient outcomes through early detection and timely treatment. Nonetheless, identifying severe cases and predicting their prognoses remain challenging. In recent years, there has been considerable interest in utilising the C-reactive protein (CRP)/albumin ratio (CAR) to evaluate the condition and forecast the prognosis of patients with sepsis. This research concentrates on the significance of CAR in the pathological process of sepsis, its association with prognosis, and the latest developments in employing procalcitonin, lactic acid, CRP, and other potential biomarkers. The CAR, with its predictive value for sepsis prognosis and mortality, is increasingly used as a clinical biochemical marker in diagnosing and monitoring patients with sepsis.
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institution Kabale University
issn 2090-2859
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publisher Wiley
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series Emergency Medicine International
spelling doaj-art-e017a120644c4a4f96418e3a73f171e22025-02-03T07:23:45ZengWileyEmergency Medicine International2090-28592024-01-01202410.1155/2024/2715606Review of the Predictive Value of Biomarkers in Sepsis MortalityNai Zhang0Yujuan Liu1Chuang Yang2Xinai Li3Department of EmergencyDepartment of EmergencyDepartment of EmergencyDepartment of Respiratory MedicineSepsis is a leading cause of mortality among severely ill individuals, primarily due to its potential to induce fatal organ dysfunction. For clinicians, it is vital to have appropriate indicators, including the physiological status and personal experiences of patients with sepsis, to monitor the condition and assess prognosis. This approach aids in preventing the worsening of the illness and reduces mortality. Recent guidelines for sepsis focus on improving patient outcomes through early detection and timely treatment. Nonetheless, identifying severe cases and predicting their prognoses remain challenging. In recent years, there has been considerable interest in utilising the C-reactive protein (CRP)/albumin ratio (CAR) to evaluate the condition and forecast the prognosis of patients with sepsis. This research concentrates on the significance of CAR in the pathological process of sepsis, its association with prognosis, and the latest developments in employing procalcitonin, lactic acid, CRP, and other potential biomarkers. The CAR, with its predictive value for sepsis prognosis and mortality, is increasingly used as a clinical biochemical marker in diagnosing and monitoring patients with sepsis.http://dx.doi.org/10.1155/2024/2715606
spellingShingle Nai Zhang
Yujuan Liu
Chuang Yang
Xinai Li
Review of the Predictive Value of Biomarkers in Sepsis Mortality
Emergency Medicine International
title Review of the Predictive Value of Biomarkers in Sepsis Mortality
title_full Review of the Predictive Value of Biomarkers in Sepsis Mortality
title_fullStr Review of the Predictive Value of Biomarkers in Sepsis Mortality
title_full_unstemmed Review of the Predictive Value of Biomarkers in Sepsis Mortality
title_short Review of the Predictive Value of Biomarkers in Sepsis Mortality
title_sort review of the predictive value of biomarkers in sepsis mortality
url http://dx.doi.org/10.1155/2024/2715606
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AT xinaili reviewofthepredictivevalueofbiomarkersinsepsismortality