Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Mitochondrial dysfunction characterises the multigenerational effects of maternal obesity on MASLD

Background & Aims: Although maternal obesity is an independent risk factor for metabolic dysfunction-associated steatotic liver disease (MASLD), the pathogenesis remains unclear. We aimed to evaluate the effect and mechanisms of multigenerational maternal Western diet (WD) on MASLD progressi...

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Bibliographic Details
Main Authors: Anneleen Heldens, Milton Antwi, Louis Onghena, Tim Meese, Yannick Gansemans, Joél Smet, Ellen Dupont, Xavier Verhelst, Sarah Raevens, Hans Van Vlierberghe, Arnaud Vanlander, Filip Van Nieuwerburgh, Lindsey Devisscher, Ruth De Bruyne, Anja Geerts, Sander Lefere
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:JHEP Reports
Subjects:
MASH
NAFLD
FGF21
Oxidative phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555925000813
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