100% oxygen mobilizes stem cells and up-regulates MIF and APRIL in humans: a new point on the hormetic dose curve

100% oxygen mobilizes stem cells and up-regulates MIF and APRIL in humans: a new point on the hormetic dose curve

IntroductionThe aim of the current study was to test normobaric 100% oxygen (NBO) (PiO2 = 713 mmHg) for stem cell mobilization and cytokine modulation. Although current oxygen therapy (PiO2 = 1,473–2,233 mmHg) is well known to mobilize stem cells and modulate cytokine, little is known about NBO and...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kent J. MacLaughlin, Gregory P. Barton, Julia E. MacLaughlin, Jacob J. Lamers, Matthew D. Marcou, Matthew J. O’Brien, Rudolf K. Braun, Marlowe W. Eldridge
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	oxygen therapy stem cell mobilization and homing inflammatory cyotokines macrophage migration inhibition factor hematopoietic (stem cell) transplant (HSCT) proangiogenic
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1377203/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Modified screening and management strategies for chronic rhinosinusitis in hematologic patients receiving hematopoietic stem cell transplantation
by: Yen-Hui Lee, et al.
Published: (2025-02-01)

Haploidentical hematopoietic stem cell transplantation using post-transplant cyclophosphamide in patients with inborn errors of immunity: Experience in a reference center in Colombia
by: Diego Medina, et al.
Published: (2024-12-01)

MSCs with upregulated lipid metabolism block hematopoietic stem cell differentiation via exosomal CTP-1A in MDS
by: Chunlai Yin, et al.
Published: (2025-02-01)

Hematopoietic stem cell discovery: unveiling the historical and future perspective of colony-forming units assay
by: Nur Afizah Yusoff, et al.
Published: (2025-01-01)

Dual Role of α-MSH in Colitis Progression: Mediating Neutrophil Differentiation via Bone Marrow
by: Liao X, et al.
Published: (2025-02-01)

The aging hematopoietic stem cell niche: a mini review
by: Xin Gao, et al.
Published: (2025-02-01)

Clinical Characteristics and Prognostic Factors Affecting Clinical Outcomes in Cytomegalovirus Retinitis Following Allogeneic Hematopoietic Stem Cell Transplantation
by: Qiaozhu Zeng, et al.
Published: (2025-01-01)

Effect of Hematopoietic Stem Cell Transplantation Regimen on Tacrolimus Pharmacokinetics
by: Haruno Oku, BS, et al.
Published: (2025-01-01)

Corrigendum: Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
by: Eun Seop Seo, et al.
Published: (2025-02-01)

Predicted indirectly recognizable HLA epitopes scores and clinical outcomes after haploidentical stem cell transplantation in pediatric patients with relapsed neuroblastoma
by: Eun Seop Seo, et al.
Published: (2025-01-01)

A concept of natural genome reconstruction. Part 2. Effect of extracellular double-stranded DNA fragments on hematopoietic stem cells
by: V. S. Ruzanova, et al.
Published: (2025-01-01)

Skeletal Site-Specific Lipid Profile and Hematopoietic Progenitors of Bone Marrow Adipose Tissue in Patients Undergoing Primary Hip Arthroplasty
by: Drenka Trivanović, et al.
Published: (2025-01-01)

Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury
by: Junjin Li, et al.
Published: (2025-03-01)

Advances in allogeneic hematopoietic stem cell transplantation for Langerhans cell histiocytosis in children
by: Guangqiang Meng, et al.
Published: (2025-01-01)

Elucidating the Role of the T Cell Receptor Repertoire in Myelodysplastic Neoplasms and Acute Myeloid Leukemia
by: Georgios Petros Barakos, et al.
Published: (2025-01-01)

ATM in immunobiology: From lymphocyte development to cancer immunotherapy
by: Ji-Hoon Lee
Published: (2025-02-01)

Haploidentical stem cell transplantation with posttransplant cyclophosphamide in children with Wiskott–Aldrich syndrome: a case report
by: Le Nguyen Ngoc Quynh, et al.
Published: (2025-02-01)

The necessity of cell banks
by: A. G. Menzorov, et al.
Published: (2017-02-01)

Injectable Tumoricidal Neural Stem Cell-Laden Hydrogel for Treatment of Glioblastoma Multiforme—An In Vivo Safety, Persistence, and Efficacy Study
by: Jasmine L. King, et al.
Published: (2024-12-01)

Cancer stem cells in head and neck squamous cell carcinoma and its associated markers: A review
by: Lavanya Mallika, et al.
Published: (2024-04-01)

Mesenchymal stem cells transplantation in the treatment of tendon disorders
by: Adrian Różycki, et al.
Published: (2025-01-01)

Impact of First- and Second-Generation Tyrosine Kinase Inhibitors on the Development of Graft-Versus-Host Disease in Individuals with Chronic Myeloid Leukemia: A Retrospective Analysis on Behalf of the Polish Adult Leukemia Group
by: Ugo Giordano, et al.
Published: (2025-01-01)

Anti-human leukocyte antigen-DPB1 antibody-associated transfusion-related acute lung injury after hematopoietic stem cell infusion
by: Mehmet Can Balkan, et al.
Published: (2024-01-01)

Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury
by: Ali Khadim, et al.
Published: (2025-02-01)

The potential of stem cell therapy in Multiple Sclerosis treatment: a review
by: Sorina Amarculesei, et al.
Published: (2023-12-01)

Stem Cell Therapy for Diseases of Livestock Animals: An In-Depth Review
by: Raghavendra B. Narasimha, et al.
Published: (2025-01-01)

Stem Cell Therapy for the Treatment of Amyotrophic Lateral Sclerosis: Comparison of the Efficacy of Mesenchymal Stem Cells, Neural Stem Cells, and Induced Pluripotent Stem Cells
by: Lauren Frawley, et al.
Published: (2024-12-01)

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD
by: Jongbok Lee, et al.
Published: (2025-01-01)

Advancements in the Treatment of Mucopolysaccharidoses: From Established Therapies to Gene Therapy
by: Joanna Wanat, et al.
Published: (2025-02-01)

Time in therapeutic range of tacrolimus in allogeneic hematopoietic stem cell transplant recipients is associated with acute graft-versus-host disease prophylaxis
by: Naoki Yoshikawa, et al.
Published: (2025-01-01)

Monocyte‐predominant engraftment, cytokine levels and early transplant‐related complications in pediatric hematopoietic stem cell recipients
by: Natalia Maximova, et al.
Published: (2019-03-01)

Innovations in intestinal organoid technology featuring an open apical surface
by: Ye Chen, et al.
Published: (2025-06-01)

Intrastromal autologous implantation of adipose derived adult stem cells for the management of established corneal scars
by: Jorge L. Alio del Barrio, et al.
Published: (2025-03-01)

The mitochondria as an emerging target of self-renewal in T-cell acute lymphoblastic leukemia
by: Majd A. Al-Hamaly, et al.
Published: (2025-12-01)

Induced mesenchymal stem cells generated from periodontal ligament fibroblast for regenerative therapy
by: Hemanathan Vembuli, et al.
Published: (2025-02-01)

Editorial: Perivascular niche and stem cell signaling in tooth
by: Takehito Ouchi, et al.
Published: (2025-01-01)

Protocol for generating human assembloids to investigate thalamocortical and corticothalamic synaptic transmission and plasticity
by: Anjana Nityanandam, et al.
Published: (2025-03-01)

MOUSE AND HUMAN EMBRYONIC STEM CELLS
by: A. G. Menzorov
Published: (2014-12-01)

Progenitor effect in the spleen drives early recovery via universal hematopoietic cell inflation
by: Takao Yogo, et al.
Published: (2025-02-01)

Protocol for the generation of HLF+ HOXA+ human hematopoietic progenitor cells from pluripotent stem cells
by: Sherry Li Zheng, et al.
Published: (2025-03-01)