Deciphering the interaction between the expression of LRP2 served as a mitochondrial metabolism-related gene and prognosis in colon cancer integrating multi-omics analysis

Deciphering the interaction between the expression of LRP2 served as a mitochondrial metabolism-related gene and prognosis in colon cancer integrating multi-omics analysis

Abstract Background Colon adenocarcinoma (COAD) is increasingly prevalent among patients under 50 years old, and the 5-year survival rate for patients with metastasis is less than 20%. Identifying significant biomarkers and therapeutic targets is crucial. We investigated the expression of LRP2 in CO...

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Bibliographic Details
Main Authors: Jie Zhang, Ziyun Liu, Xiaoqing Ma, Zhenyu Shi, Jing Zhao, Yongjie Xie, Xiaobin Shang, Xia Zhang
Format: Article
Language:English
Published: Springer 2025-05-01
Series:Discover Oncology
Subjects:
Colon cancer
Prognosis
LRP2
Multi-omics
Cell proliferation
Online Access:https://doi.org/10.1007/s12672-025-02568-2
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