Practical steps to develop a transcriptomic test for blood doping

Blood doping remains a significant problem that threatens the integrity of sport. The current indirect method for detecting blood doping involves the longitudinal measurement of an athlete’s haematological variables and identification of suspicious results that are indicative of doping (i.e., the at...

Full description

Saved in:
Bibliographic Details
Main Authors: Sutehall Shaun, Malinsky Fernanda, Voss Sven, Chester Neil, Xu Xiao, Pitsiladis Yannis
Format: Article
Language:English
Published: De Gruyter 2024-07-01
Series:Translational Exercise Biomedicine
Subjects:
Online Access:https://doi.org/10.1515/teb-2024-0010
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Blood doping remains a significant problem that threatens the integrity of sport. The current indirect method for detecting blood doping involves the longitudinal measurement of an athlete’s haematological variables and identification of suspicious results that are indicative of doping (i.e., the athlete biological passport). While this has played a significant role in the protection of clean sport, improvements are needed. The development of a transcriptomic test, that can be used to detect the use of blood doping has been discussed and researched for decades and yet, an anti-doping test that can be adopted by the World Anti-Doping Agency (WADA) is yet to be established. With recent advancements in our understanding, as well as in methods of sample collection, the possibility of a transcriptomic test that can be used by WADA, is imminent. There are, however, several practical considerations that must first be made, that will be highlighted in this perspective article.
ISSN:2942-6812