2’-FL and cross-feeding bifidobacteria reshaped the gut microbiota of infants with atopic dermatitis ex vivo and prevented dermatitis in mice post-microbiota transplantation through retinol metabolism activation

2’-FL and cross-feeding bifidobacteria reshaped the gut microbiota of infants with atopic dermatitis ex vivo and prevented dermatitis in mice post-microbiota transplantation through retinol metabolism activation

2’-Fucosyllactose (2’−FL), a predominant human milk oligosaccharide, plays a crucial role in the development of the infant gut microbiota and immune system. However, the microbiota of infants with atopic dermatitis (AD) often has difficulty utilizing 2’-FL. Here, we found that strains from human mil...

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Bibliographic Details
Main Authors: Ce Qi, Zhongxia Li, Huayu Tu, Fang Sun, Wenbo Guo, Can Di, Ruikun He, Xiaolei Ze, Lintao Zhang, Ruijuan Gao, Pengyue Hu, Wenjing Yang, Kexin Li, Jiayi Liu, Xiaonan Pan, Zilu Jin, Jin Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
2’-fucosyllactose
bifidobacteria
atopic dermatitis
retinol metabolism
cross-feeding
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2474148
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