Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection
The implementation of safe and maximally effective ovarian stimulation is a major aim for in vitro fertilization (IVF) teams. The goal of controlled ovarian hyperstimulation (COH) is to supply enough oocytes with normal maturation to insure the consequent biological procedures. A variety of differen...
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| Format: | Article |
| Language: | English |
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Wiley
2006-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2006.145 |
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| author | Tanya Timeva Tanya Milachich Irena Antonova Tanya Arabaji Atanas Shterev Hatim A. Omar |
| author_facet | Tanya Timeva Tanya Milachich Irena Antonova Tanya Arabaji Atanas Shterev Hatim A. Omar |
| author_sort | Tanya Timeva |
| collection | DOAJ |
| description | The implementation of safe and maximally effective ovarian stimulation is a major aim for in vitro fertilization (IVF) teams. The goal of controlled ovarian hyperstimulation (COH) is to supply enough oocytes with normal maturation to insure the consequent biological procedures. A variety of different stimulation protocols have been suggested and an individual selection of the correct stimulation protocol is mandatory. The aim of the present study is to evaluate the correlation between number of retrieved oocytes and clinical pregnancy rate (CPR) after IVF or intracytoplasmic sperm injection (ICSI) procedures. We reviewed 1017 cycles in a total of 975 patients. The study results clearly demonstrate that the aspiration of less than 5 oocytes significantly reduced pregnancy rate. The aspiration of a large number of oocytes (>15) does not lead to an increase of the treatment effect and, at the same time, increases the risk of ovarian hyperstimulation syndrome. The major goal is to obtain 5—15 oocytes as a “gold standard”, connected to optimal pregnancy rate after assisted reproduction (ART). |
| format | Article |
| id | doaj-art-dfeadfc4b33f4435b3e9b02592a6b9be |
| institution | Kabale University |
| issn | 1537-744X |
| language | English |
| publishDate | 2006-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-dfeadfc4b33f4435b3e9b02592a6b9be2025-02-03T01:10:44ZengWileyThe Scientific World Journal1537-744X2006-01-01668669010.1100/tsw.2006.145Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm InfectionTanya Timeva0Tanya Milachich1Irena Antonova2Tanya Arabaji3Atanas Shterev4Hatim A. Omar5IVF Unit, Ob/Gyn Hospital “Dr. Shterev”, Sofia, BulgariaIVF Unit, Ob/Gyn Hospital “Dr. Shterev”, Sofia, BulgariaIVF Unit, Ob/Gyn Hospital “Dr. Shterev”, Sofia, BulgariaIVF Unit, Ob/Gyn Hospital “Dr. Shterev”, Sofia, BulgariaIVF Unit, Ob/Gyn Hospital “Dr. Shterev”, Sofia, BulgariaSection of Adolescent Medicine, University of Kentucky, Lexington, USAThe implementation of safe and maximally effective ovarian stimulation is a major aim for in vitro fertilization (IVF) teams. The goal of controlled ovarian hyperstimulation (COH) is to supply enough oocytes with normal maturation to insure the consequent biological procedures. A variety of different stimulation protocols have been suggested and an individual selection of the correct stimulation protocol is mandatory. The aim of the present study is to evaluate the correlation between number of retrieved oocytes and clinical pregnancy rate (CPR) after IVF or intracytoplasmic sperm injection (ICSI) procedures. We reviewed 1017 cycles in a total of 975 patients. The study results clearly demonstrate that the aspiration of less than 5 oocytes significantly reduced pregnancy rate. The aspiration of a large number of oocytes (>15) does not lead to an increase of the treatment effect and, at the same time, increases the risk of ovarian hyperstimulation syndrome. The major goal is to obtain 5—15 oocytes as a “gold standard”, connected to optimal pregnancy rate after assisted reproduction (ART).http://dx.doi.org/10.1100/tsw.2006.145 |
| spellingShingle | Tanya Timeva Tanya Milachich Irena Antonova Tanya Arabaji Atanas Shterev Hatim A. Omar Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection The Scientific World Journal |
| title | Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection |
| title_full | Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection |
| title_fullStr | Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection |
| title_full_unstemmed | Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection |
| title_short | Correlation Between Number of Retrieved Oocytes and Pregnancy Rate After In Vitro Fertilization/IntraCytoplasmic Sperm Infection |
| title_sort | correlation between number of retrieved oocytes and pregnancy rate after in vitro fertilization intracytoplasmic sperm infection |
| url | http://dx.doi.org/10.1100/tsw.2006.145 |
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