Early onset pancreatic cancer: A review
Early-onset pancreatic cancer (EOPC) is usually defined as patients with pancreatic cancer before the age of 50 years, which is relatively rare. However, the research on EOPC is somewhat obscure, and the specific clinical and molecular characteristics of this condition are debated. In this review, w...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Translational Oncology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1936523324003656 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832591876966842368 |
|---|---|
| author | Dong Luo Yixiong Li Xiao Yu Liandong Ji Xuejun Gong |
| author_facet | Dong Luo Yixiong Li Xiao Yu Liandong Ji Xuejun Gong |
| author_sort | Dong Luo |
| collection | DOAJ |
| description | Early-onset pancreatic cancer (EOPC) is usually defined as patients with pancreatic cancer before the age of 50 years, which is relatively rare. However, the research on EOPC is somewhat obscure, and the specific clinical and molecular characteristics of this condition are debated. In this review, we discussed the differences between EOPC and late-onset pancreatic cancer (LOPC) or average-onset pancreatic cancer (AOPC) with a focus on clinical and molecular characteristics, survival outcomes and treatment to promote the diagnosis and treatment of EOPC. |
| format | Article |
| id | doaj-art-dfdaabeaecc643db9f8fb295367f9fca |
| institution | Kabale University |
| issn | 1936-5233 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Translational Oncology |
| spelling | doaj-art-dfdaabeaecc643db9f8fb295367f9fca2025-01-22T05:41:26ZengElsevierTranslational Oncology1936-52332025-02-0152102239Early onset pancreatic cancer: A reviewDong Luo0Yixiong Li1Xiao Yu2Liandong Ji3Xuejun Gong4Department of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; Department of General, Visceral and Transplant Surgery, European Pancreas Centre, Heidelberg. University Hospital, Heidelberg, GermanyDepartment of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, ChinaDepartment of Hepatopancreatobiliary Surgery Ⅱ, Third Xiangya Hospital, Central South University, Changsha, 410013, ChinaDepartment of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; Corresponding authors at: Department of Pancreatic Surgery/ National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China.Department of Pancreatic Surgery, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China; Corresponding authors at: Department of Pancreatic Surgery/ National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, China.Early-onset pancreatic cancer (EOPC) is usually defined as patients with pancreatic cancer before the age of 50 years, which is relatively rare. However, the research on EOPC is somewhat obscure, and the specific clinical and molecular characteristics of this condition are debated. In this review, we discussed the differences between EOPC and late-onset pancreatic cancer (LOPC) or average-onset pancreatic cancer (AOPC) with a focus on clinical and molecular characteristics, survival outcomes and treatment to promote the diagnosis and treatment of EOPC.http://www.sciencedirect.com/science/article/pii/S1936523324003656Early-onset pancreatic cancerClinical characteristicsMolecular characteristicsSurvival outcomes |
| spellingShingle | Dong Luo Yixiong Li Xiao Yu Liandong Ji Xuejun Gong Early onset pancreatic cancer: A review Translational Oncology Early-onset pancreatic cancer Clinical characteristics Molecular characteristics Survival outcomes |
| title | Early onset pancreatic cancer: A review |
| title_full | Early onset pancreatic cancer: A review |
| title_fullStr | Early onset pancreatic cancer: A review |
| title_full_unstemmed | Early onset pancreatic cancer: A review |
| title_short | Early onset pancreatic cancer: A review |
| title_sort | early onset pancreatic cancer a review |
| topic | Early-onset pancreatic cancer Clinical characteristics Molecular characteristics Survival outcomes |
| url | http://www.sciencedirect.com/science/article/pii/S1936523324003656 |
| work_keys_str_mv | AT dongluo earlyonsetpancreaticcancerareview AT yixiongli earlyonsetpancreaticcancerareview AT xiaoyu earlyonsetpancreaticcancerareview AT liandongji earlyonsetpancreaticcancerareview AT xuejungong earlyonsetpancreaticcancerareview |