Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT
Small-animal single-photon emission computed tomography-X-ray computed tomography (SPECT-CT) is an advanced imaging tool for preclinical research of single-photon radiopharmaceuticals. Its detection performance is the foundation of image quality and the reliability of experimental data. This study a...
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Editorial Board of Journal of Isotopes
2025-02-01
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| Series: | Journal of Isotopes |
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| Online Access: | https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.066 |
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| author | Jie TANG Dong XU Qianyue HU Bo ZHANG Wei LI Lizhen WANG Huixin YU Fukuan ZHAO |
| author_facet | Jie TANG Dong XU Qianyue HU Bo ZHANG Wei LI Lizhen WANG Huixin YU Fukuan ZHAO |
| author_sort | Jie TANG |
| collection | DOAJ |
| description | Small-animal single-photon emission computed tomography-X-ray computed tomography (SPECT-CT) is an advanced imaging tool for preclinical research of single-photon radiopharmaceuticals. Its detection performance is the foundation of image quality and the reliability of experimental data. This study aims to evaluate the performance of Albira SI SPECT-CT in terms of advisable test range，linearity，stability，deviation of measurement results，related to the radioactive isotope 99mTc，and to explore the authenticity and reliability of the scan results.The Albira SI SPECT-CT was subjected to quarterly quality control using the clinically commonly used single-photon radionuclide 99mTc. The linearity，stability，and deviation of the measurement results were tested，and preliminary attempts were made at small-animal bone metabolism scanning. The device demonstrated a strong linear correlation between radioactivity and measurement results，exhibited high stability，and showed minimal variation when compared to commonly used radioactivity measurement devices.The Albira SI small animal SPECT-CT accurately reflects the distribution of the radioactive activity of the single photon isotope 99mTc，showing excellent imaging of mouse bone metabolism，suitable for preclinical radiopharmaceutical research. The method for evaluating SPECT-CT performance established in this study is expected to provide a reference for the operation of similar equipment. |
| format | Article |
| id | doaj-art-dfcebb9391f642a399322f1d09498bd3 |
| institution | Kabale University |
| issn | 1000-7512 |
| language | zho |
| publishDate | 2025-02-01 |
| publisher | Editorial Board of Journal of Isotopes |
| record_format | Article |
| series | Journal of Isotopes |
| spelling | doaj-art-dfcebb9391f642a399322f1d09498bd32025-01-24T06:37:08ZzhoEditorial Board of Journal of IsotopesJournal of Isotopes1000-75122025-02-013819510210.7538/tws.2024.youxian.066202405066Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CTJie TANG0Dong XU1Qianyue HU2Bo ZHANG3Wei LI4Lizhen WANG5Huixin YU6Fukuan ZHAO7NHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaNHC Key Laboratory of Nuclear Medicine, Jiangsu Key Laboratory of Molecular Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Wuxi 214063, ChinaSmall-animal single-photon emission computed tomography-X-ray computed tomography (SPECT-CT) is an advanced imaging tool for preclinical research of single-photon radiopharmaceuticals. Its detection performance is the foundation of image quality and the reliability of experimental data. This study aims to evaluate the performance of Albira SI SPECT-CT in terms of advisable test range，linearity，stability，deviation of measurement results，related to the radioactive isotope 99mTc，and to explore the authenticity and reliability of the scan results.The Albira SI SPECT-CT was subjected to quarterly quality control using the clinically commonly used single-photon radionuclide 99mTc. The linearity，stability，and deviation of the measurement results were tested，and preliminary attempts were made at small-animal bone metabolism scanning. The device demonstrated a strong linear correlation between radioactivity and measurement results，exhibited high stability，and showed minimal variation when compared to commonly used radioactivity measurement devices.The Albira SI small animal SPECT-CT accurately reflects the distribution of the radioactive activity of the single photon isotope 99mTc，showing excellent imaging of mouse bone metabolism，suitable for preclinical radiopharmaceutical research. The method for evaluating SPECT-CT performance established in this study is expected to provide a reference for the operation of similar equipment.https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.066small-animal spect-ct99mtcdetection performancequality control |
| spellingShingle | Jie TANG Dong XU Qianyue HU Bo ZHANG Wei LI Lizhen WANG Huixin YU Fukuan ZHAO Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT Journal of Isotopes small-animal spect-ct 99mtc detection performance quality control |
| title | Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT |
| title_full | Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT |
| title_fullStr | Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT |
| title_full_unstemmed | Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT |
| title_short | Detection Performance of 99mTc in Albira SI Small-Animal SPECT-CT |
| title_sort | detection performance of 99mtc in albira si small animal spect ct |
| topic | small-animal spect-ct 99mtc detection performance quality control |
| url | https://tws.xml-journal.net/article/doi/10.7538/tws.2024.youxian.066 |
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