PCL/PHBV Microparticles as Innovative Carriers for Oral Controlled Release of Manidipine Dihydrochloride

PCL/PHBV Microparticles as Innovative Carriers for Oral Controlled Release of Manidipine Dihydrochloride

Microparticles of poly(ε-caprolactone) (PCL) and poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) containing manidipine dihydrochloride (MAN) were successfully prepared by the simple emulsion/solvent evaporation method. All formulations showed loading efficie...

Full description

Saved in:

Bibliographic Details
Main Authors:	Fernanda Malaquias Barboza, Willian Moreira Machado, Luiz Renato Olchanheski Junior, Josiane Padilha de Paula, Sônia Faria Zawadzki, Daniel Fernandes, Paulo Vitor Farago
Format:	Article
Language:	English
Published:	Wiley 2014-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1155/2014/268107
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Characterization and taste masking evaluation of microparticles with cetirizine dihydrochloride and methacrylate-based copolymer obtained by spray drying
by: Amelian Aleksandra, et al.
Published: (2017-03-01)

Controlled Release of Ropivacaine from Single-Armed (1-PCL) and Four-Armed PCL (4-PCL) Microspheres
by: Wei Xiong, et al.
Published: (2019-01-01)

Characterization of PCL and Chitosan Nanoparticles as Carriers of Enoxaparin and Its Antithrombotic Effect in Animal Models of Venous Thrombosis
by: Lucas Bessa Prado, et al.
Published: (2017-01-01)

Optimized Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) Production by Moderately Haloalkaliphilic Bacterium Halomonas alkalicola Ext
by: Martin N. Muigano, et al.
Published: (2024-01-01)

Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration
by: Francisca L. Gomes, et al.
Published: (2025-01-01)

Simultaneous Determination of Paracetamol, Acetyl Salicylic Acid, Mefenamic Acid and Cetirizine Dihydrochloride in the Pharmaceutical Dosage Form
by: Freddy H. Havaldar, et al.
Published: (2010-01-01)

Circulating Endothelial Microparticles in Diabetes Mellitus
by: A. F. Tramontano, et al.
Published: (2010-01-01)

Spectral Characterization and Crystal Structure of 1,2-Bis-(1H-benzimidazol-2-yl)-ethane Dihydrochloride
by: Aydin Tavman, et al.
Published: (2013-01-01)

Preparation of PAN Spinning Solution with Fine Dispersion of Cellulose Microparticles
by: Jee-Woo Yang, et al.
Published: (2015-01-01)

Circulating Endothelial Microparticles: A Key Hallmark of Atherosclerosis Progression
by: Keshav Raj Paudel, et al.
Published: (2016-01-01)

Rod-Shaped Magnetite Nano/Microparticles Synthesis at Ambient Temperature
by: Balaprasad Ankamwar, et al.
Published: (2013-01-01)

Oxidative stability of sacha inchi oil microparticles covered with ovalbumin
by: Ermelindo de Souza Silva Neto, et al.
Published: (2025-01-01)

Heat Treatment Effect on Some Mechanical Properties of FDM-Manufactured PCL Wood-Based Biopolymer
by: Irina Beșliu-Băncescu, et al.
Published: (2024-01-01)

Passive Posterior Tibial Subluxation on Routine Knee MRI as a Secondary Sign of PCL Tear
by: Andrew J. Degnan, et al.
Published: (2014-01-01)

Synthesis and Evaluation of PCL/Chitosan/CQD‐Fe Magnetic Nanocomposite for Wound Healing: Emphasis on Gene Expression
by: Elham Maghareh Abed, et al.
Published: (2025-01-01)

Enhanced Cell Proliferation, Migration, and Fibroblast Differentiation with Electrospun PCL–Zinc Scaffolds Coated with Fibroblast-Derived ECM
by: Alexis Moody, et al.
Published: (2025-01-01)

Evaluation of Single-Bundle versus Double-Bundle PCL Reconstructions with More Than 10-Year Follow-Up
by: Masataka Deie, et al.
Published: (2015-01-01)

Oyster Shell Powder/PCL Composite Scaffolds Loaded with Psoralen Nanospheres Promote Large Bone Defect Repair
by: Tianpeng Liu, et al.
Published: (2025-01-01)

Eco-friendly alginate/PCL-TiO2 hybrid biocomposites: Preparation, properties, and methylene blue photodegradation
by: Bunga Fisikanta Bukit, et al.
Published: (2025-01-01)

Natural-Based Microparticles as Sole Stabilizers of High Internal Phase Pickering Emulsions
by: Marie Cafiero, et al.
Published: (2025-01-01)

Effect of Thrombolysis on Circulating Microparticles in Patients with ST-Segment Elevation Myocardial Infarction
by: Zhe Li, et al.
Published: (2023-01-01)

Production of Lipid Microparticles Magnetically Active by a Supercritical Fluid-Based Process
by: Keti Vezzù, et al.
Published: (2009-01-01)

Picosecond Laser Etching of Glass Spiral Microfluidic Channel for Microparticles Dispersion and Sorting
by: Rong Chen, et al.
Published: (2025-01-01)

Radial self-accelerating acoustic beam for three-dimensional helical motion of microparticles
by: Di-Chao Chen, et al.
Published: (2025-01-01)

Preparation of Antheraea pernyi Silk Fibroin Microparticles through a Facile Electrospinning Method
by: Xiufang Li, et al.
Published: (2016-01-01)

Nonlinearities in Drug Release Process from Polymeric Microparticles: Long-Time-Scale Behaviour
by: Elena Simona Bacaita, et al.
Published: (2012-01-01)

Preparation and In Vitro Evaluation of Alginate Microparticles Containing Amphotericin B for the Treatment of Candida Infections
by: Merlis P. Alvarez-Berrios, et al.
Published: (2020-01-01)

Fabrication of Core-Shell PLGA-Chitosan Microparticles Using Electrospinning: Effects of Polymer Concentration
by: Nguyen Thi Hiep, et al.
Published: (2017-01-01)

Resveratrol-loaded PCL-PEG/GO/HAP biocomposite bone membranes: Evaluation of mechanical properties, release kinetics, and cellular response
by: Betül Meryem Arpacay, et al.
Published: (2025-02-01)

Macroporous Composite Cryogels with Embedded Polystyrene Divinylbenzene Microparticles for the Adsorption of Toxic Metabolites from Blood
by: Tanja Eichhorn, et al.
Published: (2013-01-01)

Improvements in the Rheological Properties, Impact Strength, and the Biodegradability of PLA/PCL Blend Compatibilized by Electron-Beam Irradiation in the Presence of a Reactive Agent
by: Jae Sung Jeon, et al.
Published: (2018-01-01)

Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
by: A. Jiménez-Periáñez, et al.
Published: (2013-01-01)

Pectin-Coated Curcumin-Chitosan Microparticles Crosslinked with Mg2+ for Delayed Drug Release in the Digestive System
by: Seung Won Hwang, et al.
Published: (2018-01-01)

Cyclic Voltammetry and Oxidation Rate Studies of Ferrous Gluconate Complex Solutions for Preparation of Chitosan-Tripolyphosphate Microparticles
by: Noer Abyor Handayani, et al.
Published: (2020-01-01)

Sustained release biodegradable solid lipid microparticles: Formulation, evaluation and statistical optimization by response surface methodology
by: Hanif Muhammad, et al.
Published: (2017-12-01)

Preparation of Starch/Gelatin Blend Microparticles by a Water-in-Oil Emulsion Method for Controlled Release Drug Delivery
by: Theeraphol Phromsopha, et al.
Published: (2014-01-01)

The effect of containing Al2O3 microparticles in different matrix polymers on properties of pineapple fiber-reinforced composites
by: Indra Mawardi, et al.
Published: (2024-01-01)

Uji Diagnostik Pemeriksaan Sifilis Metode Chemiluminescence Microparticle Immunoassay (CMIA) terhadap Treponema Pallidum Haemaglutination Assay (TPHA)
by: Erina Dwi Kumalasari, et al.
Published: (2023-11-01)

Janus arcú művészet: technikai tudás és költői ihletettség Platón költészetértelmezésében
by: Emese Faragó
Published: (2014-10-01)

Career management to carrier advice
by: Ilić Đurđijana, et al.
Published: (2019-01-01)