Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2025-03-01
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| Series: | JACS Au |
| Online Access: | https://doi.org/10.1021/jacsau.4c01268 |
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| _version_ | 1849394372863328256 |
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| author | Miao Xiao Qiaoli Shang Liuyang Pu Zheyuan Wang Lei Zhu Zhen Yang Jun Huang |
| author_facet | Miao Xiao Qiaoli Shang Liuyang Pu Zheyuan Wang Lei Zhu Zhen Yang Jun Huang |
| author_sort | Miao Xiao |
| collection | DOAJ |
| format | Article |
| id | doaj-art-dfbaef36dff048cd97ebb8e76d5ab3ba |
| institution | Kabale University |
| issn | 2691-3704 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | American Chemical Society |
| record_format | Article |
| series | JACS Au |
| spelling | doaj-art-dfbaef36dff048cd97ebb8e76d5ab3ba2025-08-20T03:40:00ZengAmerican Chemical SocietyJACS Au2691-37042025-03-01531367137510.1021/jacsau.4c01268Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl EsterMiao Xiao0Qiaoli Shang1Liuyang Pu2Zheyuan Wang3Lei Zhu4Zhen Yang5Jun Huang6School of Chemistry and Chemical Engineering, University of South China, Hengyang, ChinaSchool of Chemistry and Chemical Engineering, University of South China, Hengyang, ChinaSchool of Chemistry and Chemical Engineering, University of South China, Hengyang, ChinaState Key Laboratory of Chemical Oncogenomics and Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, ChinaCollege of Pharmacy, Third Military Medical University, Chongqing, ChinaState Key Laboratory of Chemical Oncogenomics and Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, ChinaSchool of Chemistry and Chemical Engineering, University of South China, Hengyang, Chinahttps://doi.org/10.1021/jacsau.4c01268 |
| spellingShingle | Miao Xiao Qiaoli Shang Liuyang Pu Zheyuan Wang Lei Zhu Zhen Yang Jun Huang Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester JACS Au |
| title | Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester |
| title_full | Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester |
| title_fullStr | Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester |
| title_full_unstemmed | Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester |
| title_short | Photoredox-Catalyzed Radical Cyclization of Unactivated Alkene-Substituted β‑Ketoesters Enabled Asymmetric Total Synthesis of Tricyclic Prostaglandin D2 Metabolite Methyl Ester |
| title_sort | photoredox catalyzed radical cyclization of unactivated alkene substituted β ketoesters enabled asymmetric total synthesis of tricyclic prostaglandin d2 metabolite methyl ester |
| url | https://doi.org/10.1021/jacsau.4c01268 |
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