Exploring Chemokine Homodimer Stability: Structural Insights into CXC and CC Interfaces

Exploring Chemokine Homodimer Stability: Structural Insights into CXC and CC Interfaces

Chemokine ligands play a pivotal role in immune response by mediating cell migration and coordinating cellular processes through interactions with chemokine receptors. Understanding their sequence and structural integrity is crucial for elucidating their biological functions and potential therapeuti...

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Bibliographic Details
Main Authors: David Budean, Yasser Almeida-Hernández, Jitendra Pandey, Joel Mieres Pérez, Elsa Sánchez García, Ellinor Haglund
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biophysica
Subjects:
chemokines
homodimer
dimer interface
protein–protein interaction
conformational dynamics
protein folding
Online Access:https://www.mdpi.com/2673-4125/4/4/37
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