Identifying Lactylation-related biomarkers and therapeutic drugs in ulcerative colitis: insights from machine learning and molecular docking

Identifying Lactylation-related biomarkers and therapeutic drugs in ulcerative colitis: insights from machine learning and molecular docking

Abstract Background Ulcerative colitis (UC), a chronic relapsing-remitting inflammatory bowel disease. Recent studies have shown that lactylation modifications may be involved in metabolic-immune interactions in intestinal inflammation through epigenetic regulation, but their specific mechanisms in...

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Bibliographic Details
Main Authors: Yao Yang, Xu Sun, Bin Liu, Yunshu Zhang, Tong Xie, Junchen Li, Jifeng Liu, Qingkai Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Pharmacology and Toxicology
Subjects:
Ulcerative colitis
Lactylation
Machine learning
Biomarkers
Molecular docking
Online Access:https://doi.org/10.1186/s40360-025-00939-7
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