An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects

Structured lipids have attracted significant interest in industries, such as food, pharmaceuticals, and cosmetics, because they can be alternatives to traditional lipids. Enzymatic synthesis techniques utilizing lipases have gained attention for structured lipids synthesis because of their site and...

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Main Authors: Chi Rac Hong, Byeong Jun Jeon, Kyung-Min Park, Eun Ha Lee, Sung-Chul Hong, Seung Jun Choi
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2023/1222373
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author Chi Rac Hong
Byeong Jun Jeon
Kyung-Min Park
Eun Ha Lee
Sung-Chul Hong
Seung Jun Choi
author_facet Chi Rac Hong
Byeong Jun Jeon
Kyung-Min Park
Eun Ha Lee
Sung-Chul Hong
Seung Jun Choi
author_sort Chi Rac Hong
collection DOAJ
description Structured lipids have attracted significant interest in industries, such as food, pharmaceuticals, and cosmetics, because they can be alternatives to traditional lipids. Enzymatic synthesis techniques utilizing lipases have gained attention for structured lipids synthesis because of their site and substrate specificity. However, most lipases discovered to date exhibit sn-1,3 regiospecificity or nonspecificity, limiting the selective range of natural oils and fats that can be used as raw materials. In this review, we provide an overview of the current synthesis methods and applications of structured lipids and the limitations of existing lipases in producing structured lipids. In addition, we discuss innovative approaches, including metagenomics, and machine learning, to discover, and classify new lipases and the use of gene editing technologies for lipase engineering. These efforts aim to overcome the limitations of existing lipases and expand the range of natural oils and fats that can be used for the production of structured lipids. Therefore, this study aims to promote a better understanding of structured lipids as a material with high-added value and provides insight into ongoing research efforts in the field.
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spelling doaj-art-dfa6a10b58dd4f179d18ebf579a8f5512025-02-03T01:29:34ZengWileyJournal of Chemistry2090-90712023-01-01202310.1155/2023/1222373An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future ProspectsChi Rac Hong0Byeong Jun Jeon1Kyung-Min Park2Eun Ha Lee3Sung-Chul Hong4Seung Jun Choi5Department of Food Science and TechnologySmart Farm Research CenterDepartment of Food Science and BiotechnologySmart Farm Research CenterDepartment of Food Science and BiotechnologyDepartment of Food Science and TechnologyStructured lipids have attracted significant interest in industries, such as food, pharmaceuticals, and cosmetics, because they can be alternatives to traditional lipids. Enzymatic synthesis techniques utilizing lipases have gained attention for structured lipids synthesis because of their site and substrate specificity. However, most lipases discovered to date exhibit sn-1,3 regiospecificity or nonspecificity, limiting the selective range of natural oils and fats that can be used as raw materials. In this review, we provide an overview of the current synthesis methods and applications of structured lipids and the limitations of existing lipases in producing structured lipids. In addition, we discuss innovative approaches, including metagenomics, and machine learning, to discover, and classify new lipases and the use of gene editing technologies for lipase engineering. These efforts aim to overcome the limitations of existing lipases and expand the range of natural oils and fats that can be used for the production of structured lipids. Therefore, this study aims to promote a better understanding of structured lipids as a material with high-added value and provides insight into ongoing research efforts in the field.http://dx.doi.org/10.1155/2023/1222373
spellingShingle Chi Rac Hong
Byeong Jun Jeon
Kyung-Min Park
Eun Ha Lee
Sung-Chul Hong
Seung Jun Choi
An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
Journal of Chemistry
title An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
title_full An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
title_fullStr An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
title_full_unstemmed An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
title_short An Overview of Structured Lipid in Food Science: Synthesis Methods, Applications, and Future Prospects
title_sort overview of structured lipid in food science synthesis methods applications and future prospects
url http://dx.doi.org/10.1155/2023/1222373
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