Alteration in Indole Metabolites After Cardiopulmonary Bypass Surgery in Neonates and Infants

Alteration in Indole Metabolites After Cardiopulmonary Bypass Surgery in Neonates and Infants

IMPORTANCE:. Cardiopulmonary bypass (CPB) surgery is associated with changes in the intestinal microbiome. Metabolism of tryptophan into the indole pathway is entirely facilitated by the intestinal microbiome, and indole metabolites play a critical role in intestinal epithelial integrity, intestinal...

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Main Authors: Matthew K. Leroue, MD, Aline B. Maddux, MD, MSCS, Tanner Lehmann, BS, Sierra Niemiec, MS, Christopher A. Mancuso, PhD, Ludmila Khailova, PhD, Peter M. Mourani, MD, Jelena Klawitter, PhD, Jesse A. Davidson, MD, MPH
Format: Article
Language:English
Published: Wolters Kluwer 2025-05-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000001267
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