A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor

Central airway obstruction (CAO) is generally defined as airflow limitation due to >50 % occlusion and is most commonly due to malignant etiologies. However, benign etiologies, including herpes-simplex-virus (HSV) endobronchial pseudotumor, can occur. Due to the rarity of HSV causing airway obstr...

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Main Authors: Alan Hyslop, Robert Weller
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007124001345
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author Alan Hyslop
Robert Weller
author_facet Alan Hyslop
Robert Weller
author_sort Alan Hyslop
collection DOAJ
description Central airway obstruction (CAO) is generally defined as airflow limitation due to >50 % occlusion and is most commonly due to malignant etiologies. However, benign etiologies, including herpes-simplex-virus (HSV) endobronchial pseudotumor, can occur. Due to the rarity of HSV causing airway obstruction, an evidence-based approach to the bronchoscopic resection and standardization of therapy after removal are lacking. Herein, we present a case of HSV pseudotumor successfully managed by argon-plasma-coagulation (APC) debulking via bronchoscopy and medical management with intravenous foscarnet due to failed treatment with acyclovir for previous HSV lesions.
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spelling doaj-art-df8dba54ec9a4c29a461f18ce57e445d2025-08-20T02:49:53ZengElsevierRespiratory Medicine Case Reports2213-00712024-01-015210211110.1016/j.rmcr.2024.102111A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumorAlan Hyslop0Robert Weller1Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, USA; Indiana University School of Medicine, Indianapolis, IN, USA; Corresponding author. Methodist Hospital MPC Building Suite 230, 1801 N Senate Blvd, Indianapolis, IN, 46202, USA.Division of Pulmonary, Critical Care, Sleep and Occupational Medicine, USA; Indiana University School of Medicine, Indianapolis, IN, USACentral airway obstruction (CAO) is generally defined as airflow limitation due to >50 % occlusion and is most commonly due to malignant etiologies. However, benign etiologies, including herpes-simplex-virus (HSV) endobronchial pseudotumor, can occur. Due to the rarity of HSV causing airway obstruction, an evidence-based approach to the bronchoscopic resection and standardization of therapy after removal are lacking. Herein, we present a case of HSV pseudotumor successfully managed by argon-plasma-coagulation (APC) debulking via bronchoscopy and medical management with intravenous foscarnet due to failed treatment with acyclovir for previous HSV lesions.http://www.sciencedirect.com/science/article/pii/S2213007124001345Central airway obstruction (CAO)Herpes-simplex-virus (HSV) pseudotumorArgon plasma coagulation (APC)Human immunodeficiency virus (HIV)
spellingShingle Alan Hyslop
Robert Weller
A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
Respiratory Medicine Case Reports
Central airway obstruction (CAO)
Herpes-simplex-virus (HSV) pseudotumor
Argon plasma coagulation (APC)
Human immunodeficiency virus (HIV)
title A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
title_full A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
title_fullStr A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
title_full_unstemmed A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
title_short A sheep in wolf's clothing? Herpes-simplex-virus endobronchial pseudotumor
title_sort sheep in wolf s clothing herpes simplex virus endobronchial pseudotumor
topic Central airway obstruction (CAO)
Herpes-simplex-virus (HSV) pseudotumor
Argon plasma coagulation (APC)
Human immunodeficiency virus (HIV)
url http://www.sciencedirect.com/science/article/pii/S2213007124001345
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