Native RNA nanopore sequencing reveals antibiotic-induced loss of rRNA modifications in the A- and P-sites
Abstract The biological relevance and dynamics of mRNA modifications have been extensively studied; however, whether rRNA modifications are dynamically regulated, and under which conditions, remains unclear. Here, we systematically characterize bacterial rRNA modifications upon exposure to diverse a...
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| Main Authors: | Anna Delgado-Tejedor, Rebeca Medina, Oguzhan Begik, Luca Cozzuto, Judith López, Sandra Blanco, Julia Ponomarenko, Eva Maria Novoa |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-024-54368-x |
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