The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis
Objective: Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease. There are studies suggesting that childhood traumas cause hypothalamic-pituitary-adrenal axis dysfunction in adulthood, which predisposes patients to autoimmune diseases. Our study aimed to investigate the relatio...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2024-01-01
|
| Series: | Gazi Medical Journal |
| Subjects: | |
| Online Access: | https://gazimedj.com/articles/the-role-of-childhood-traumas-in-adult-hashimotos-thyroiditis/doi/gmj.galenos.2023.4024 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850028758769074176 |
|---|---|
| author | Uğur Aydoğan Hüseyin Demirci Ebru Aydoğan |
| author_facet | Uğur Aydoğan Hüseyin Demirci Ebru Aydoğan |
| author_sort | Uğur Aydoğan |
| collection | DOAJ |
| description | Objective: Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease. There are studies suggesting that childhood traumas cause hypothalamic-pituitary-adrenal axis dysfunction in adulthood, which predisposes patients to autoimmune diseases. Our study aimed to investigate the relationship between HT and childhood trauma.
Methods: In our study, we included 52 patients diagnosed with HT and 31 healthy controls and evaluated the Turkish Childhood Trauma Questionnaire (which evaluates childhood traumas retrospectively) in both groups. The diagnosis of HT was confirmed using anti-thyroid peroxi-dase (anti-TPO) levels and thyroid ultrasonography.
Results: The childhood emotional neglect score (10.79±3.90) was significantly higher in pa-tients with HT than in the control group (p=0.04). However, no significant difference was ob-served between the two groups regarding other components. In addition, a significant positive correlation was found between anti-TPO levels and emotional neglect score (p=0.02; r=0.26).
Conclusion: The significantly higher emotional neglect score in patients with HT compared with the control group and the positive correlation between childhood emotional neglect score and anti-TPO level suggest that childhood traumas may play a role in the etiology of adult HT. Further and large-scale studies are needed to elucidate all aspects of this subject. |
| format | Article |
| id | doaj-art-df5eea160f9347328178dc257c284cc7 |
| institution | DOAJ |
| issn | 2147-2092 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Gazi Medical Journal |
| spelling | doaj-art-df5eea160f9347328178dc257c284cc72025-08-20T02:59:45ZengGalenos Publishing HouseGazi Medical Journal2147-20922024-01-01351697410.12996/gmj.galenos.2023.4024The Role of Childhood Traumas in Adult Hashimoto’s ThyroiditisUğur Aydoğan0https://orcid.org/0000-0002-8942-9991Hüseyin Demirci1https://orcid.org/0000-0003-0737-2360Ebru Aydoğan2https://orcid.org/0009-0005-7939-742XAnkara Etlik City Hospital, Clinic of Intensive Care, Ankara, TürkiyeAnkara Etlik City Hospital, Clinic of Endocrinology and Metabolism, Ankara, TürkiyeHacettepe University Hospitals, Clinic of Public Health, Ankara, TürkiyeObjective: Hashimoto’s thyroiditis (HT) is the most common autoimmune thyroid disease. There are studies suggesting that childhood traumas cause hypothalamic-pituitary-adrenal axis dysfunction in adulthood, which predisposes patients to autoimmune diseases. Our study aimed to investigate the relationship between HT and childhood trauma. Methods: In our study, we included 52 patients diagnosed with HT and 31 healthy controls and evaluated the Turkish Childhood Trauma Questionnaire (which evaluates childhood traumas retrospectively) in both groups. The diagnosis of HT was confirmed using anti-thyroid peroxi-dase (anti-TPO) levels and thyroid ultrasonography. Results: The childhood emotional neglect score (10.79±3.90) was significantly higher in pa-tients with HT than in the control group (p=0.04). However, no significant difference was ob-served between the two groups regarding other components. In addition, a significant positive correlation was found between anti-TPO levels and emotional neglect score (p=0.02; r=0.26). Conclusion: The significantly higher emotional neglect score in patients with HT compared with the control group and the positive correlation between childhood emotional neglect score and anti-TPO level suggest that childhood traumas may play a role in the etiology of adult HT. Further and large-scale studies are needed to elucidate all aspects of this subject.https://gazimedj.com/articles/the-role-of-childhood-traumas-in-adult-hashimotos-thyroiditis/doi/gmj.galenos.2023.4024autoimmune thyroiditishashimoto’s thyroiditischildhood traumas |
| spellingShingle | Uğur Aydoğan Hüseyin Demirci Ebru Aydoğan The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis Gazi Medical Journal autoimmune thyroiditis hashimoto’s thyroiditis childhood traumas |
| title | The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis |
| title_full | The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis |
| title_fullStr | The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis |
| title_full_unstemmed | The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis |
| title_short | The Role of Childhood Traumas in Adult Hashimoto’s Thyroiditis |
| title_sort | role of childhood traumas in adult hashimoto s thyroiditis |
| topic | autoimmune thyroiditis hashimoto’s thyroiditis childhood traumas |
| url | https://gazimedj.com/articles/the-role-of-childhood-traumas-in-adult-hashimotos-thyroiditis/doi/gmj.galenos.2023.4024 |
| work_keys_str_mv | AT uguraydogan theroleofchildhoodtraumasinadulthashimotosthyroiditis AT huseyindemirci theroleofchildhoodtraumasinadulthashimotosthyroiditis AT ebruaydogan theroleofchildhoodtraumasinadulthashimotosthyroiditis AT uguraydogan roleofchildhoodtraumasinadulthashimotosthyroiditis AT huseyindemirci roleofchildhoodtraumasinadulthashimotosthyroiditis AT ebruaydogan roleofchildhoodtraumasinadulthashimotosthyroiditis |